552299-77-1Relevant articles and documents
Aza-bridged bicyclic amine derivatives for use as novel cholinergic receptor ligands
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Page 7-8, (2008/06/13)
The present invention discloses novel cholinergic receptor ligands. The present invention also relates to the synthesis of substituted derivatives of aza-bridged bicyclic amines for use as muscarinic receptor ligands as well as methods of regulating funct
C(8) substituted 1-azabicyclo[3.3.1]non-3-enes and C(8) substituted 1-azabicyclo[3.3.1]nonan-4-ones: Novel muscarinic receptor antagonists
Kim, Myoung Goo,Bodor, Erik T.,Wang, Chen,Harden, T. Kendall,Kohn, Harold
, p. 2216 - 2226 (2007/10/03)
Expedient syntheses of C(8) substituted 1-azabicyclo[3.3.1]non-3-enes and C(8) substituted 1-azabicyclo[3.3.1]nonan-4-ones are reported to begin with 2,5-disubstituted pyridines. Catalytic reduction of the pyridine to the piperidine followed by treatment