552856-57-2

Upstream product

• 552856-52-7 5-O-benzoyl-4-C-benzoyloxymethyl-3-O-benzyl-1,2-O-isopropylidene-α-D-erythro-pentofuranose 
• 552856-54-9 1,2-di-O-acetyl-5-O-benzoyl-4-C-benzoyloxymethyl-3-O-benzyl-D-erythro-pentofuranose 
• 63593-03-3 1,2-O-isopropylidene-3-O-benzyl-4-hydroxymethyl-α-D-ribofuranose 
• 98-88-4 benzoyl chloride 
• 552856-56-1 1-(2-O-acetyl-5-O-benzoyl-4-C-benzoyloxymethyl-3-O-benzyl-β-D-erythro-pentofuranosyl)thymine 

Downstream Products

• 552856-58-3 2,2-anhydro-1-(5-O-benzoyl-4-C-benzoyloxymethyl-3-O-benzyl-β-D-threo-pentofuranosyl)thymine 
• 552856-59-4 1-(3-O-benzyl-5-O-benzoyl-4-C-benzoyloxymethyl-β-D-threo-pentofuranosyl)thymine 
• 552856-61-8 6-(2-azido-3-O-benzyl-2-deoxy-5-O-benzoyl-4-C-(benzoyloxymethyl)-β-D-erythro-pentofuranosyl)-tetrazolo[1,5-c]pyrimidin-8-methyl-5(6H)-one 
• 219601-01-1 (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-hydroxy-5-methyl-3-(thymin-1-yl)-2-oxa-5-azabicyclo[2.2.1]heptane 
• 552856-44-7 (1R,3R,4R,7S)-7-benzyloxy-1-hydroxymethyl-3-(thymin-1-yl)-2-oxa-5-azabicyclo[2.2.1]heptane 
• 552856-48-1 (1R,3R,4R,7S)-7-benzyloxy-1-hydroxymethyl-5-methyl-3-(thymin-1-yl)-2-oxa-5-azabicyclo[2.2.1]heptane 
• 552856-42-5 (1R,3R,4R,7S)-7-benzyloxy-1-methanesulfonyloxymethyl-3-(thymin-1-yl)-2-oxa-5-azabicyclo[2.2.1]heptane 
• 625111-32-2 (1R,3R,4R,7S)-7-benzyloxy-1-methanesulfonyloxymethyl-5-methyl-3-(thymin-1-yl)-2-oxa-5-azabicyclo[2.2.1]heptane 
• 552856-43-6 (1R,3R,4R,7S)-1-benzoyloxymethyl-7-benzyloxy-3-(thymin-1-yl)-2-oxa-5-azabicyclo[2.2.1]heptane 
• 552856-41-4 1-[2-azido-3-O-benzyl-2-deoxy-5-O-methanesulfonyl-4-C-(methanesulfonyloxymethyl)-β-D-erythro-pentofuranosyl]thymine 
• 1054637-17-0 (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-hydroxy-5-N-methyl-3-(4-amino-5-methyl-cytosine-1-yl)-2-oxa-5-azabicyclo[2:2:1]heptane 
• 1053315-55-1 Acetic acid (1R,3R,4R,7S)-1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-methyl-3-(5-methyl-2-oxo-4-[1,2,4]triazol-1-yl-2H-pyrimidin-1-yl)-2-oxa-5-aza-bicyclo[2.2.1]hept-7-yl ester 
• 552856-49-2 (1R,3R,4R,7S)-(4,4'-dimethoxytrityloxymethyl)-7-hydroxy-5-methyl-3-(4-benzoyl-5-methylcytosin-1-yl)-2-oxa-5-azabicyclo[2.2.1]heptane 

Relevant academic research and scientific papers

Synthesis of 2′-amino-LNA: A new strategy

In this paper we present revised and significantly improved synthetic routes to 2′-amino-LNA (locked nucleic acid). The optimal route is convergent with the synthesis of LNA monomers ("2′-oxy-LNA") via a common intermediate obtained by a mild deacetylatio