552890-65-0Relevant articles and documents
Synthesis of the JKLM-ring fragment of ciguatoxin
Baba, Takayuki,Huang, Guobin,Isobe, Minoru
, p. 6851 - 6872 (2007/10/03)
A stereoselective synthesis of the LM-ring fragment has been achieved starting from a sugar derivative. A stereoselective synthesis of the JKLM-ring fragment has been achieved through a coupling between two segments via heteroconjugate addition, seven-membered ether ring formation mediated by an acetylene cobalt complex, and spiroketalization reaction.