55321-98-7

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dimethylbenzamide is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,6-Dimethylbenzamide is utilized as an intermediate for the production of various agrochemicals, including pesticides and herbicides. Its properties contribute to the effectiveness and performance of these products in agricultural applications.
Used in Organic Synthesis:
2,6-Dimethylbenzamide is used as a building block in organic synthesis for the preparation of a wide range of aromatic compounds. Its versatility and reactivity make it an essential component in the synthesis of various organic molecules for different industries.
Used in Research and Development:
Due to its unique properties and reactivity, 2,6-Dimethylbenzamide is also used in research and development for the exploration of new chemical reactions and the synthesis of novel compounds. Its applications in this field contribute to the advancement of scientific knowledge and the discovery of new materials and products.

Upstream product

• 6575-13-9 2,6-dimethylbenzonitrile 
• 108-38-3 m-xylene 
• 51-79-6 urethane 
• 103-84-4 Acetanilid 
• 4406-41-1 N-phenylisobutyramide 
• 621-06-7 2,N-diphenylacetamide 
• 40669-47-4 N-methyl-N,2-diphenylacetamide 
• 87-62-7 2,6-dimethylaniline 
• 130403-08-6 D₂₉₁₆ 
• 21900-37-8 2,6-dimethylbenzoyl chloride 
• 124808-91-9 2,6-Dimethylbenzoylurea 

Downstream Products

• 632-46-2 2,6-dimethylbenzoic acid 
• 93161-81-0 2,6-dimethyl-benzoic acid-(3-diethylamino-propylamide) 
• 94329-95-0 2,6-dimethyl-benzoic acid-(2-diethylamino-propylamide) 
• 7251-82-3 3-Methylphthalimide 
• 65399-02-2 7-Methyl-2,3-dihydroisoindole-1-one 
• 20642-93-7 methyl (2,6-dimethylphenyl)carbamate 
• 527-61-7 2,6-dimethyl-1,4-benzoquinone 

Relevant academic research and scientific papers

Gold Activation of Nitriles: Catalytic Hydration to Amides

A gold-based catalytic system that efficiently mediates the hydration of a broad spectrum of nitriles, including aromatic, heteroaromatic and aliphatic examples and efficiently catalyze the hydration of a range of organonitriles has been reported. Nitriles are considered inert in the context gold catalysis and have only been used as reaction solvent or as throw-away ligands in well-defined cationic gold catalysis. The obtained product was purified by flash chromatography using a gradient of pentane/ethyl acetate and compound 1 was isolated as a colorless solid. Aromatic substrates bearing two nitrile groups as in rn-benzenedinitrile and p-benzenedinitrile underwent double nitrile hydration and afforded excellent yields in the corresponding diamides. There is high relevance for the use of cationic gold complexes bearing such ligands and should have important implications in catalysis.

Chemical oxidation of an anticonvulsant N-(5'-methylisoxazol-3-yl) 2,6- dimethylbenzamide (D2916)

The new anticonvulsant N-(5'-methylisoxazol-3-yl)-2,6-dimethylbeazamide (D2916), which presents two kinds of methyl groups which could be oxidized, was submitted to various chemical oxidizing agents. Several sites and degrees of oxidation were observed. The main oxidized site was the arylmethyl group without cleavage of the isoxazole ring, leading via carboxylic acid and primary alcohol intermediates to phthalimide and lactame derivatives. In no case was the methyl group of the isoxazole moiety hydroxylated.

A versatile synthesis of amidines from nitriles via amidoximes

Benzamidines were prepared conveniently from benzonitriles in good yield via catalytic hydrogenation of intermediate benzamidoximes in acetic acid/acetic anhydride.