5533-05-1Relevant academic research and scientific papers
Regioselective Fluorination of Acenes: Tailoring of Molecular Electronic Levels and Solid-State Properties
Bischof, Daniel,Tripp, Matthias W.,Hofmann, Philipp E.,Ip, Chun-Ho,Ivlev, Sergei I.,Gerhard, Marina,Koert, Ulrich,Witte, Gregor
, (2022/01/08)
Optoelectronic properties of molecular solids are important for organic electronic devices and are largely determined by the adopted molecular packing motifs. In this study, we analyzed such structure-property relationships for the partially regioselectiv
Cationic Alkynyl Heck Reaction toward Substituted Allenes Using BobCat: A New Hybrid Pd(0)-Catalyst Incorporating a Water-Soluble dba Ligand
Neff, Robynne K.,Frantz, Doug E.
supporting information, p. 17428 - 17432 (2019/01/04)
The cationic alkynyl Heck reaction between aryl triflates and alkynes to give substituted allenes is described. Key to the success of this method was the discovery and development of a new hybrid Pd(0)-catalyst, BobCat, that incorporates a water-soluble dba-ligand and biaryl phosphine ligand to provide substituted allenes in good yields under mild reaction conditions.
BITTER TASTE MODULATORS
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Page/Page column 97, (2012/01/06)
The present invention includes antagonists of human type 2 taste receptors (hT2Rs) having structural Formula (I). The present invention also provides compositions containing these antagonists, the use of these antagonists for modulating taste perception, particularly bitter taste, and the method of preparing these antagonists (I).
Pt(IV)-catalyzed generation and [4+2]-cycloaddition reactions of o-quinone methides
Radomkit, Suttipol,Sarnpitak, Pakornwit,Tummatorn, Jumreang,Batsomboon, Paratchata,Ruchirawat, Somsak,Ploypradith, Poonsakdi
supporting information; experimental part, p. 3904 - 3914 (2011/06/22)
Novel intermolecular and intramolecular generations of ortho-quinone methides and their formal [4+2]-cycloaddition reactions with olefins catalyzed by PtCl4 and AuCl3 under mild conditions have been developed. Good to excellent yields (up to 99%) and diastereoselectivity (up to >99:1) of the chromans were obtained. PtCl4 was found to be effective and compatible with various functional groups present in the substrates. A mechanism accounting for its catalytic cycle is proposed and discussed.
Generation of ortho-quinone methides by p-TsOH on silica and their hetero-Diels-Alder reactions with styrenes
Batsomboon, Paratchata,Phakhodee, Wong,Ruchirawat, Somsak,Ploypradith, Poonsakdi
supporting information; experimental part, p. 4009 - 4012 (2009/10/14)
(Chemical Equation Presented) 2-Arylchromans were readily prepared from the hetero-Diels-Alder reactions of styrenes with the ortho-quinone methides (o-QMs) which, in turn, were generated by treating the MOM-protected benzylacetate derivatives with p-TsOH immobilized on silica (PTS-Si) in toluene under mild conditions (0°C to rt). The corresponding chromans were obtained in moderate to excellent yields (42-97%) and in moderate to excellent diastereoselectivity (up to >99:1).
Synthesis of a new series of chiral tri- and tetradentate ligands and their application in titanium-catalyzed pinacol coupling reaction
Chatterjee,Joshi
, p. 1475 - 1482 (2008/09/18)
A variety of chiral tridentate and tetradentate ligands, related to each other through stereoelectronic relationship have been synthesized. Homochiral diols and amino alcohols have been used for this purpose. Titanium complexes of these ligands have been prepared and examined for enantioselective pinacol coupling reaction.
Highly enantioselective aza-Morita-Baylis-Hillman reaction with a bisphenol-based bifunctional organocatalyst
Ito, Katsuji,Nishida, Kanako,Gotanda, Takashi
, p. 6147 - 6149 (2008/03/12)
Newly developed phosphino-bisphenol 1c was found to be an efficient organocatalyst for the aza-Morita-Baylis-Hillman reaction. High enantioselectivity up to 96% ee was obtained with catalyst loading of 1 mol %.
Bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof
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Page/Page column 31, (2010/01/31)
Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds have the structural formula (I): in which Ar1 is a radical having one of the structural formulae (a)-(c): Ar2 is a radical having one of the following formulae (d)-(h): and X is a radical having one of the following formulae (i)-(l): and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.
Radicicol derivatives
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, (2008/06/13)
Radicicol derivatives represented by the following formula (I) having tyrosine kinase inhibition activity or pharmacologically acceptable salts thereof: wherein R1and R2are the same or different, and each represents hydrogen, alkanoy
