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Ethyl 3-[4-(diethylamino)phenyl]isoxazole-4-carboxylate is a complex organic compound with the chemical formula C16H20N2O3. It is a derivative of isoxazole, a heterocyclic aromatic organic compound, and features a phenyl group substituted with a diethylamino group. This molecule is characterized by its potential applications in pharmaceuticals and agrochemicals, particularly as a precursor in the synthesis of various biologically active molecules. Its structure includes an isoxazole ring fused to a phenyl ring, with a diethylamino group attached to the phenyl ring, and an ethyl carboxylate group attached to the isoxazole ring. ethyl 3-[4-(diethylamino)phenyl]isoxazole-4-carboxylate is known for its unique chemical properties and reactivity, which can be exploited in the development of new drugs and other chemical products.

5533-25-5

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5533-25-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5533-25-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,3 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5533-25:
(6*5)+(5*5)+(4*3)+(3*3)+(2*2)+(1*5)=85
85 % 10 = 5
So 5533-25-5 is a valid CAS Registry Number.

5533-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 3-[4-(diethylamino)phenyl]-1,2-oxazole-4-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:5533-25-5 SDS

5533-25-5Relevant academic research and scientific papers

Hydrothiolation of unactivated alkynes catalyzed by indium(III) bromide

Yadav,Reddy, B. V. Subba,Raju,Ravindar,Baishya, Gakul

, p. 1474 - 1475 (2008/03/14)

Indium(III) bromide is found to catalyze efficiently the hydrothiolation of unactivated alkynes with various thiols under mild conditions to produce the corresponding dithioacetals in excellent yields. However, addition of aromatic thiols on aromatic alky

Nucleophilic α-addition to β-nitroacrylates: application to the synthesis of α-thioacrylates

Lewandowska, Elzbieta

, p. 4879 - 4883 (2007/10/03)

The α-addition of alkyl or aryl thionucleophiles to β-nitro-α,β-unsaturated alkenoates in THF in the presence of TEA or DBU gave access to the α-thio-α,β-unsaturated alkenoates. The reaction occurred via formation of β-nitro-α-thioalkanoates and concomitant elimination of nitrous acid from the α-adducts.

1,2-Thio group migration in Rh(II) carbene reactions

Xu, Feng,Shi, Weifeng,Wang, Jianbo

, p. 4191 - 4194 (2007/10/03)

A series of β-thio group substituted α-diazo carbonyl compounds have been prepared by nucleophilic substitution reactions of thiophenol, thionaphthol, or benzyl mercaptan with β-acetoxy-α-diazo carbonyl compounds. The diazo decomposition of these diazo ca

Microwave-assisted tandem nucleophilic substitution-Wittig reaction of α-hypervalent iodine functionalized phosphonium ylide

Yu, Xiaochun,Huang, Xian

, p. 1895 - 1897 (2007/10/03)

Under microwave irradiation conditions the tandem nucleophilic substitution-Wittig reaction of α-hypervalent iodine functionalized phosphonium ylide can occur readily to afford α-heteroatom substituted-α,β-unsaturated enoates in good yields stereo-selecti

Reaction of 1-Lithio-1-arylthio(or alkylthio)methyltrimethylsilane with Acid Derivatives. A Novel Synthesis of Functionalized Vinyl Sulfides

Agawa, Toshio,Ishikawa, Minori,Komatsu, Mitsuo,Ohshiro, Yoshiki

, p. 1205 - 1208 (2007/10/02)

Reactions of 1-lithio-1-phenylthiomethyl- (1a) and 1-lithio-1-methylthiomethyltrimethylsilane (1b) with amides, an ester, acid anhydrides, a urea, and a carbonate are described which provide useful routes to functionalized vinyl sulfides.The reaction of 1 with amides gave β-functionalized vinyl sulfides, 1-dialkylamino-2-phenylthio (or methylthio)ethylenes, in 40-95percent yields and the reaction could be extended to the sulfonyl derivatives of 1 to afford 1-dialkylamino-2-phenylsulfonyl(or methylsulfonyl)ethylenes.Although ethyl benzoate and some acid anhydrides were not good substrates for this reaction, tetramethylurea and diethyl carbonate gave α-functionalized vinyl sulfides, 1-amidovinyl- and 1-(ethoxycarbonyl)vinyl sulfides, in moderate yields when treated with 1a followed by addition of benzaldehyde.

Regiochemical Control of the Addition of Aryl Selenols and Aryl Thiols to the Triple Bond of Arylpropiolates. Synthesis of Seleno- and Thioflavones and Seleno- and Thioaurones

Wadsworth, Donald H.,Detty, Michael R.

, p. 4611 - 4615 (2007/10/02)

Addition of aryl selenols and aryl thiols to arylpropiolates under basic conditions followed by saponification gave exclusively β-substituted cinnamates of predominant Z sterochemistry.Neat solutions of aryl selenols or aryl thiols and arylpropiolates aft

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