55331-32-3

Upstream product

• 49769-48-4 3-formyl-7-(thien-2-ylacetamido)-2-cephem-4-carboxylic acid 
• 908093-98-1 diazodiphenylmethane 

Downstream Products

• 61225-25-0 (6R)-3-((Ξ)-1-hydroxy-propyl)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2ξ-carboxylic acid benzhydryl ester 
• 55243-95-3 (6R)-3-((Ξ)-1-hydroxy-ethyl)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2ξ-carboxylic acid benzhydryl ester 
• 61282-47-1 (6R)-3-((Ξ)-1-benzoyloxy-ethyl)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2ξ-carboxylic acid benzhydryl ester 
• 55570-03-1 (6R)-3-methylcarbamoyl-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2c-carboxylic acid benzhydryl ester 
• 55569-96-5 (6R)-3-[(methyl-oxy-imino)-methyl]-5ξ,8-dioxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 55570-04-2 (6R)-3-(acetyl-methyl-carbamoyl)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2c-carboxylic acid benzhydryl ester 
• 55570-02-0 (6R)-3-((3Ξ)-4ξ-methoxycarbonyl-2-methyl-isoxazolidin-3r-yl)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 55570-00-8 (6R)-3-((Ξ)-2-methyl-5-oxo-4-phenyl-[1,2,4]oxadiazolidin-3-yl)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 55570-01-9 (6R)-3-((3Ξ)-4ξ-methoxycarbonyl-2-methyl-isoxazolidin-3r-yl)-5ξ,8-dioxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 55569-99-8 (6R)-3-((Ξ)-2-methyl-5-oxo-4-phenyl-[1,2,4]oxadiazolidin-3-yl)-5ξ,8-dioxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 55569-98-7 (Ξ)-2-[(6R)-2-benzhydryloxycarbonyl-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-3-yl]-3-methyl-2,3-dihydro-oxazole-4,5-dicarboxylic acid dimethyl ester 
• 55569-97-6 (Ξ)-2-[(6R)-2-benzhydryloxycarbonyl-5ξ,8-dioxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-en-3-yl]-3-methyl-2,3-dihydro-oxazole-4,5-dicarboxylic acid dimethyl ester 
• 55570-07-5 (6R)-3-formyl-4-methylamino-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2t-carboxylic acid benzhydryl ester 
• 55570-06-4 (6R)-3-formyl-4-methylamino-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2c-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

7-Acylamino-3-acyl-2(or 3)cephems

Intermediate C-3 1-hydroxyalkyl or 1-hydroxyarylalkyl cephems, prepared by reacting Grignard reagents at low temperature with 3-formyl-2-cephem compounds, are oxidized to the corresponding 7-acylamino-3-acyl-2(or 3)cephem-4-carboxylic acids and esters thereof, which are useful as antibiotics or as intermediates in preparing antibiotic substances.

Substituted sulfonylacetamido cephalosporins

Cephalosporin compounds having various substituted sulfonylacetamido groups at position 7 have been prepared and have antibacterial activity.