55360-45-7

Basic information

• Product Name: Benzenemethanol, 3-methoxy-a-(3-methoxyphenyl)-
• Synonyms: di(m-methoxyphenyl)methyl alcohol;bis-(3-methoxy-phenyl)-methanol;3,3'-dimethoxybenzhydrol;3,3'-Dimethoxy-benzhydrol
• CAS NO: 55360-45-7
• Molecular Formula: C15H16O3
• Molecular Weight: 244.29
• Mol File: 55360-45-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 210 - 212 °C (6 mmHg)
• Density: 1.135±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanol, 3-methoxy-a-(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3-methoxy-a-(3-methoxyphenyl)-(55360-45-7)
• EPA Substance Registry System: Benzenemethanol, 3-methoxy-a-(3-methoxyphenyl)-(55360-45-7)

Safety Data

• Hazardous Substances Data: 55360-45-7(Hazardous Substances Data)

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 109-94-4 formic acid ethyl ester 
• 2845-89-8 1-chloro-3-methoxy-benzene 
• 591-31-1 3-methoxy-benzaldehyde 
• 124-38-9 carbon dioxide 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 31600-88-1 m-methoxyphenyllithium 

Downstream Products

• 39193-85-6 3,3'-dimethoxybenzophenone 
• 1622071-23-1 C₁₇H₁₈O₄ 
• 189567-33-7 di(3-methoxyphenyl)methyl bromide 
• 112895-98-4 6-Methoxy-4-(3-methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoline 
• 112896-01-2 1-{6-(4-Chloro-butoxy)-4-[3-(4-chloro-butoxy)-phenyl]-3,4-dihydro-1H-isoquinolin-2-yl}-ethanone 
• 112895-99-5 1-[(R)-6-Methoxy-4-(3-methoxy-phenyl)-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone 
• 112896-00-1 1-[(R)-6-Hydroxy-4-(3-hydroxy-phenyl)-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone 
• 112965-88-5 (-)-6-methoxy-4-(3-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 112896-01-2 (-)-N-acetyl-6-(4-chlorobutoxy)-4-<3-(4-chlorobutoxy)phenyl>-1,2,3,4-tetrahydroisoquinoline 
• 113260-28-9 bis(3-methoxyphenyl)<(trimethylsily)oxy>acetonitrile 
• 112895-99-5 (-)-N-acetyl-6-methoxy-4-(3-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 112896-00-1 (-)-N-acetyl-6-hydroxy-4-(3-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 112895-98-4 6-Methoxy-4-(3-methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoline 
• 112895-96-2 N-(tert-butyloxycarbonyl)-N-(hydroxymethyl)-2,2-bis(3-methoxyphenyl)ethylamine 

Relevant articles and documents

A Bisphenolic Honokiol Analog Outcompetes Oral Antimicrobial Agent Cetylpyridinium Chloride via a Membrane-Associated Mechanism

Targeting Streptococcus mutans is the primary focus in reducing dental caries, one of the most common maladies in the world. Previously, our groups discovered a potent bactericidal biaryl compound that was inspired by the natural product honokiol. Herein, a structure activity relationship (SAR) study to ascertain structural motifs key to inhibition is outlined. Furthermore, mechanism studies show that bacterial membrane disruption is central to the bacterial growth inhibition. During this process, it was discovered that analog C2 demonstrated a 4-fold better therapeutic index compared to the commercially available antimicrobial cetylpyridinium chloride (CPC) making it a viable alternative for oral care.

CoI-Catalyzed Barbier Reactions of Aromatic Halides with Aromatic Aldehydes and Imines

The reductive Barbier coupling of aromatic halides and electrophiles has been achieved using a CoBr2/1,10-phenanthroline catalytic system and over stoichiometric amounts of zinc. The reaction displayed a broad scope of substrates, including (hetero)aryl chlorides as pro-nucleophiles and aldehydes or imines as electrophiles, leading to diarylmethanols and diarylmethylamines in moderate to excellent yields, respectively.

UV light-mediated difunctionalization of alkenes through aroyl radical addition/1,4-/1,2-Aryl shift cascade reactions

UV light-mediated difunctionalization of alkenes through an aroyl radical addition/1,4-/1,2-aryl shift has been described. The resulted aroyl radical from a photocleavage reaction added to acrylamide compounds followed by cyclization led to the formation of oxindoles, whereas the addition to cinnamic amides aroused a unique 1,4-aryl shift reaction. Furthermore, the difunctionalization of alkenes of prop-2-en-1-ols was also achieved through aroyl radical addition and a sequential 1,2-aryl shift cascade reaction.