55400-73-2

Basic information

• Product Name: 1,11-BIS(METHANESULFONYLOXY)-3,6,9-TRIOXANDECANE
• Synonyms: 1,11-BIS(METHANESULFONYLOXY)-3,6,9-TRIOXANDECANE;3,6,9,12-Tetraoxa-13-thiatetradecan-1-ol 1-Methanesulfonate 13,13-Dioxide;MS-PEG4-MS;Ms-PEG5-Ms
• CAS NO: 55400-73-2
• Molecular Formula: C₁₀H₂₂O₉S₂
• Molecular Weight: 350.40628
• Product Categories: Nitric Oxide Reagents;Cross Linking Reagents
• Mol File: 55400-73-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 533.6°C at 760 mmHg
• Flash Point: 276.5°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 6.3E-11mmHg at 25°C
• Refractive Index: 1.47
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Solubility: Dichloromethane
• CAS DataBase Reference: 1,11-BIS(METHANESULFONYLOXY)-3,6,9-TRIOXANDECANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,11-BIS(METHANESULFONYLOXY)-3,6,9-TRIOXANDECANE(55400-73-2)
• EPA Substance Registry System: 1,11-BIS(METHANESULFONYLOXY)-3,6,9-TRIOXANDECANE(55400-73-2)

Safety Data

• Hazardous Substances Data: 55400-73-2(Hazardous Substances Data)

Usage

Description

Ms-PEG5-Ms are PEG linkers containing two mesyl moieties. The mesyl groups are good leaving groups and can also be used as protecting groups for primary alcohols. They can be deprotected in the presence of sodium amalgam. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Chemical Properties

Yellow Oil

InChI:InChI=1/C10H22O9S2/c1-20(11,12)18-9-7-16-5-3-15-4-6-17-8-10-19-21(2,13)14/h3-10H2,1-2H3

Upstream product

• 914311-67-4 N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-5-(dimethylamino)naphthalene-1-sulfonamide 
• 124-63-0 methanesulfonyl chloride 
• 112-60-7 Tetraethylene glycol 

Downstream Products

• 1469479-27-3 2,2-[oxybis(2,1-ethanediyloxy-2,1-ethanediyloxy)]bis(4-methylbenzaldehyde) 
• 1333107-40-6 3-(4-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxy)phenyl)-7-methoxyisoquinolin-1(2H)-one 
• 75832-82-5 <3,5>-dibenzo-24-crown-8 
• 133560-78-8 <2,5>-dibenzo-21-crown-7 
• 14174-08-4 benzo-12-crown-4 
• 1356146-38-7 N-[9-(2-[(14-azido-2-oxo-6,9,12-trioxa-3-azatetradec-1-yl)(1-methylethyl)carbamoyl]phenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium chloride 
• 66750-09-2 16-phenyl-1,4,7,10,13-pentaoxa-16-azacycloheptadecane 
• 1268488-02-3 C₂₁H₂₉N₅O₇S 
• 65883-12-7 2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl methanesulfonate 
• 39557-70-5 4'-Vinylbenzo-15-crown-5 ether 
• 41757-95-3 2-Acetyl-6,7,9,10,12,13,15,16-octahydro-1,4,7,10,13-pentaoxabenzocyclopentadecene 
• 134179-38-7 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethylamine 
• 524728-93-6 C₆₄H₈₆O₉ 
• 99314-01-9 25,27-(3,6,9-trioxaundeca-1,11-diyl)oxy-26,28-dihydroxy-5,11,17,23-tetra-tert-butyl-calix[4]arene 

Relevant articles and documents

A convenient route to diversely substituted icosahedral closomer nanoscaffolds

The design and synthesis of icosahedral polyhedral borane closomer motifs based upon carbonate and carbamate anchoring groups for biomedical applications are described. Dodecacarbamate closomers containing easily accessible groups of interest at their linker termini were synthesized via activation of the B-OH vertices as aryl carbonates and their subsequent reaction with primary amines. Novel dodecacarbonate closomers were successfully synthesized for the first time by reacting [closo-B12(OH)12]2- with an excess of respective aryl chloroformates, utilizing relatively short reaction times, mild conditions and simple purification strategies, all of which had previously presented difficulties in closomer chemistry. This methodology for the 12-fold degenerate synthesis of carbonate and carbamate closomers will greatly facilitate further exploration of closomers as monodisperse nanomolecular delivery platforms.