55417-80-6

Basic information

• Product Name: 4-HYDROXY-6-METHYL-2-(2-PYRIDYL)PYRIMIDINE
• Synonyms: 4-HYDROXY-6-METHYL-2-(2-PYRIDYL)PYRIMIDINE;6-METHYL-2-(2-PYRIDINYL)-4-PYRIMIDINOL;BUTTPARK 14\02-53;4-Hydroxy-6-methyl-2-(pyridin-2-yl)pyrimidine, 2-(4-Hydroxy-6-methyl-1,3-diazin-2-yl)pyridine
• CAS NO: 55417-80-6
• Molecular Formula: C10H9N3O
• Molecular Weight: 187.2
• Mol File: 55417-80-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 114-116°
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-HYDROXY-6-METHYL-2-(2-PYRIDYL)PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-6-METHYL-2-(2-PYRIDYL)PYRIMIDINE(55417-80-6)
• EPA Substance Registry System: 4-HYDROXY-6-METHYL-2-(2-PYRIDYL)PYRIMIDINE(55417-80-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 55417-80-6(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-6-methyl-2-(2-pyridyl)pyrimidine is a complex organic compound that belongs to the class of organic compounds known as hydroxypyrimidines. They are compounds containing a pyrimidine ring, which is a six-membered heterocyclic aromatic ring with two nitrogen atoms and four carbon atoms, substituted at least at one carbon atom with a hydroxyl group. 4-Hydroxy-6-methyl-2-(2-pyridyl)pyrimidine, specifically, has a pyrimidine ring attached to a pyridyl group, with the additional characteristic of a hydroxyl group substitution. This chemical shows prominence in various research activities, particularly—it is used in synthetic applications within chemical laboratories. However, the toxicity level, environmental impact, and broader uses of this chemical are not well-documented in the available literature.

Upstream product

• 88136-80-5 6-Methyl-2-pyridin-2-yl-[1,3]thiazin-4-one 
• 100-70-9 2-Cyanopyridine 
• 51285-26-8 pyridine-2-carboxamidine hydrochloride 
• 141-97-9 ethyl acetoacetate 
• 52313-50-5 pyridine-2-carboxamidine 
• 2524-52-9 ethyl-2-picolinate 
• 15846-25-0 ethyl ester of β-aminocrotonic acid 
• 77168-60-6 pyridine-2-carboxamidinium benzenesulfonate 

Downstream Products

• 77168-31-1 4-chloro-6-methyl-2-(2-pyridinyl)pyrimidine 

Relevant articles and documents

Studies on ketene and its derivatives. LXXVII. Reaction of diketene with pyridineformimidates and related compounds to give 1,3 oxazin 4 one derivatives

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POTASSIUM CHANNEL MODULATORS

Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with potassium channels. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with potassium channels.

Preparation method and application of phosphorescence iridium complexes with mitochondrial targeting function

The invention discloses phosphorescence iridium complexes with a mitochondrial targeting function, and a preparation method thereof, and an application thereof in biological imaging and oxygen detection. The complexes are composed of a cyclic metal ligand, a metal center and an auxiliary ligand containing a mitochondrial targeting function group, and the structure of the complexes is represented by a general formula shown in the description; the luminous intensity and the emission life of the complexes reduce with the increase of the oxygen concentration; mitochondria of living cells are marked; the change of the concentration of oxygen in the mitochondria of living cells is detected through a confocal imaging and life imaging technology; and the phosphorescence iridium complexes have important application prospect in biological imaging and sensing fields.

A convenient synthesis of pyrimidinone and pyrimidine containing bisheteroarenes and analogs

The synthesis of pyrimidinone containing bisheteroarenes (3) and related analogs (9 and 10) by the reaction of active methylenes or substituted methyl acrylate with nitrogen containing precursors viz. amidines, or thiourea in water as well as other organic solvents was studied. Synthesized compounds have further been explored for the synthesis of diversified pyrimidines 4, 6-8, 11, 12 and 14 through a sequential approach. This journal is the Partner Organisations 2014.