55438-67-0

Usage

Chemical compound

A chemical compound with potential pharmaceutical applications.

Pyrrolidine derivative

Contains a diphenylmethyl group and an azetidinyl ring.

Psychoactive drug potential

Has been studied for its potential use as a psychoactive drug.

Treatment for neurological and psychiatric disorders

May have potential as a treatment for various neurological and psychiatric disorders.

Applications in pharmaceutical development

May have applications in the development of new pharmaceuticals for treating conditions such as anxiety, depression, and schizophrenia.

Interaction with neurotransmitter systems

Unique chemical structure gives it the potential to interact with specific neurotransmitter systems in the brain.

Interest for further research and development

Of interest for further research and development in the pharmaceutical industry.

Upstream product

• 18621-17-5 1-(diphenylmethyl)-3-hydroxyazetidine 
• 123-75-1 pyrrolidine 
• 33301-41-6 1-benzhydryl-3-azetidinyl methanesulfonate 

Relevant academic research and scientific papers

A Single-Step Synthesis of Azetidine-3-amines

The azetidine group is frequently encountered within contemporary medicinal chemistry. However, the introduction of an azetidine can be synthetically challenging. Herein, a straightforward synthesis of azetidine-3-amines, starting from a bench stable, commercial material is presented. The reaction tolerates common functionality and proceeds in moderate-to-high yield with secondary amines, and moderate-to-low yield with primary amines. The methodology compares favorably to alternative procedures and can be utilized in "any-stage"functionalization, including late-stage azetidinylation of approved drugs and other compounds with pharmacological activity.

Hydrazinopyrimidines as cysteine protease inhibitors

Substituted heteroaryl nitrile derivatives of Formula I, processes for their preparation, pharmaceutical compositions comprising such compounds and use of the compounds as cysteine protease inhibitors are provided.

Thiophene derivatives useful as anticancer agents

The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt and to pharmaceutically acceptable salts and hydrates thereof, wherein X, Y, R1, R2 and R11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.

Quantitative structure-activity relationships of antibacterial agents, 7-heterocyclic amine substituted 1-cyclopropyl-6,8-difluoro-4-oxoquinoline-3-carboxylic acids

Quantitative structure-activity relationships (QSAR) of various 7-(3-substituted-azetidin-1-yl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro -4-oxoquinoline-3-carboxylic acids, 14-25, were studied to clarify the structural requirements for 3-substituted azetidi