554449-47-7

Basic information

• Product Name: 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzamide
• Synonyms: 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzamide
• CAS NO: 554449-47-7
• Molecular Weight: 338.433
• Mol File: 554449-47-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzamide(554449-47-7)
• EPA Substance Registry System: 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzamide(554449-47-7)

Safety Data

• Hazardous Substances Data: 554449-47-7(Hazardous Substances Data)

Upstream product

• 454464-55-2 rac-3-(2-bromo-propionyl)-benzoic acid methyl ester 
• 115006-21-8 3-propionyl-benzoic acid methyl ester 
• 74380-71-5 3-hydroxycarbonyl-propiophenone 
• 50916-34-2 3-propionylbenzonitrile 
• 19829-31-3 1-(3-bromophenyl)-1-propanone 
• 454464-86-9 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzoic acid methyl ester 

Relevant articles and documents

N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action

The synthesis of a series of N-aminoimidazoles (NAIMs) with an uncommon spectrum of antiretroviral activity is described. From a group of 60 closely related molecules, we were able to subdivide the molecules in different groups based on their anti-HIV and anti-SIV activity in vitro: (i) molecules acting on a new, immediate postintegration step, (ii) molecules acting on both postintegration and HIV-1 reverse transcriptase (RT) as NNRTI, and (iii) molecules that mainly act at the HIV-1 RT according to an NNRTI-type mode of action.