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554451-61-5

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554451-61-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 554451-61-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,4,4,5 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 554451-61:
(8*5)+(7*5)+(6*4)+(5*4)+(4*5)+(3*1)+(2*6)+(1*1)=155
155 % 10 = 5
So 554451-61-5 is a valid CAS Registry Number.

554451-61-5Relevant articles and documents

Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Duan, James J.-W.,Chen, Lihua,Lu, Zhonghui,Jiang, Bin,Asakawa, Naoyuki,Sheppeck II, James E.,Liu, Rui-Qin,Covington, Maryanne B.,Pitts, William,Kim, Soong-Hoon,Decicco, Carl P.

, p. 266 - 271 (2007/10/03)

Using a pyrimidine-2,4,6-trione motif as a zinc-binding group, a series of selective inhibitors of tumor necrosis factor-α converting enzyme (TACE) was discovered. Optimization of initial lead 1 resulted in a potent inhibitor (51), with an IC50

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