55446-81-6Relevant academic research and scientific papers
Transfer hydrogenation reactions catalyzed by chiral half-sandwich Ruthenium complexes derived from Proline
Pandia Kumar, Arun Kumar,Samuelson, Ashoka G
, p. 1405 - 1415 (2016/09/19)
Chiral ruthenium half-sandwich complexes were prepared using a chelating diamine made from proline with a phenyl, ethyl, or benzyl group, instead of hydrogen on one of the coordinating arms. Three of these complexes were obtained as single diastereoisomers and their configuration identified by X-ray crystallography. The complexes are recyclable catalysts for the reduction of ketones to chiral alcohols in water. A ruthenium hydride species is identified as the active species by NMR spectroscopy and isotopic labelling experiments. Maximum enantio-selectivity was attained when a phenyl group was directly attached to the primary amine on the diamine ligand derived from proline. [Figure not available: see fulltext.]
Synthesis of 6, desGly10>GnRH-Et without Side-Chain Protection
Masiukiewicz, E.,Rzeszotarska, B.,Wiejak, S.
, p. 674 - 680 (2007/10/02)
A gonadoliberin superagonist, 6, desGly1>GnRH-Et* (5), was obtained in solution by connecting segments, Glp-His-Trp-Ser-Tyr-N2H3 (1) and Z-DSer(tBu)-LeuArg(AcOH)-Pro-NHEt (4) (Scheme 1), which were produced witho
INHIBITORS OF PANCREATIC AND LEUKOCYTE ELASTASE
Kasafirek, Evzen,Fric, Premysl,Slaby, Jan,Kocna, Petr
, p. 3034 - 3041 (2007/10/02)
Tho following alkylamides of ω-carboxyalkanoyldi- and tripeptides of the Ala-Pro or Ala-Ala-Pro sequence have been prepared: ethylamide-, propylamide-, and isobutylamide of 3-carboxypropionylalanyl-proline, ethylamide of 3-carboxypropionylalanyl-alanyl-pr
SYNTHESIS OF BIOLOGICALLY ACTIVE ANALOGS OF LULIBERIN WITH SHORTENED AMINO ACID SEQUENCES
Burov, S. V.,Nikolaev, S. V.,Smironova, M. P.,Lupanova, G. E.,Bobrov, Yu. F.,et al.
, p. 732 - 737 (2007/10/02)
Two new analogs of the releasing factor of the luteinizing hormone with shortened amino acid sequences have been synthesized by the methods of classical peptide chemistry.The influence of the preparations on the action of chorionic gonadotropin and on the
