55478-53-0Relevant academic research and scientific papers
Calycosin derivative as well as preparation method and application thereof
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Paragraph 0028; 0029' 0030, (2017/01/02)
The invention relates to a calycosin derivative as well as a preparation method and application thereof, belonging to the field of medicinal chemistry. The calycosin derivative is of a structure A shown in the specification, wherein R1 and R2 are out one
Amino acid adducts for percutaneous delivery of vitamin B3
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Page/Page column 4, (2008/06/13)
The present invention relates to adducts of an amino acid or of a peptide with a vitamin B3 compound. Such adducts, thanks to the amino acid chain, easily penetrate the skin and are able to efficiently deliver the vitamin B3 compound to when applied topic
Haem d1: Development of a new coupling procedure leading to the synthesis of isobacteriochlorins
Mackman, Richard L.,Micklefield, Jason,Block, Michael H.,Leeper, Finian J.,Battersby, Alan R.
, p. 2111 - 2122 (2007/10/03)
A new approach has been developed for construction of the western and eastern lactams, e.g. 2 and 3, needed for synthesis of isobacteriochlorins. It involves acylation of pyrroles with lactonic acids to form ketones. These are then efficiently converted into the desired lactams by a short sequence of reactions. All the steps are high yielding and simple to carry out.
