55507-06-7Relevant articles and documents
Copper(II/I) complexes of 5-pyridin-2-yl-[1,3]dioxolo[4,5-g]isoquinoline: Synthesis, crystal structure, antitumor activity and DNA interaction
Huang, Ke-Bin,Chen, Zhen-Feng,Liu, Yan-Cheng,Wang, Meng,Wei, Jian-Hua,Xie, Xiao-Li,Zhang, Jian-Lian,Hu, Kun,Liang, Hong
, p. 640 - 648 (2013)
Three new copper(II) complexes of 5-pyridin-2-yl-[1,3]dioxolo[4,5-g] isoquinoline (PYP), i.e. [Cu2(PYP)2Cl4] (1), [Cu4(PYP)4(ClO4)2(H 2O)2](ClO4)
Direct Amidation of Carboxylic Acids through an Active α-Acyl Enol Ester Intermediate
Xu, Xianjun,Feng, Huangdi,Huang, Liliang,Liu, Xiaohui
, p. 7962 - 7969 (2018/06/18)
The development of a highly efficient and simple protocol for the direct amidation of carboxylic acids is described employing ynoates as novel coupling reagents. The transformation proceeds in good to excellent yields via in situ α-acyl enol ester intermediates formation under mild reaction conditions. This useful method has been demonstrated for a range of substrates to provide a succinct access to structurally diverse amides, including key intermediates of glibenclamide, tiapride hydrochloride, and nateglinide, and can be conducted on a mole scale.
Pd(II)-Catalyzed Intramolecular Tandem Olefin Amidation/C-H Activation Protocol for the Syntheses of the Protoberberine Class of Natural Products
Garad, Dnyaneshwar N.,Mhaske, Santosh B.
supporting information, p. 3862 - 3865 (2016/08/16)
A Pd(II)-catalyzed intramolecular tandem olefin amidation/C-H activation protocol has been developed for the synthesis of an 8-oxoprotoberberine core. It was successfully applied for the syntheses of (±)-8-oxocanadine, (±)-8-oxotetrahydropalmitine, and (±
