55579-70-9

Usage

Uses

Used in Organic Synthesis:
5-(2,4-DICHLOROPHENYL)CYCLOHEXANE-1,3-DIONE is utilized as a reactive intermediate in the synthesis of a variety of organic compounds. Its unique structure allows it to participate in multiple chemical reactions, facilitating the creation of new molecules with diverse applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5-(2,4-DICHLOROPHENYL)CYCLOHEXANE-1,3-DIONE is studied for its potential biological and pharmacological activities. It has shown promise as an anti-inflammatory and antitumor agent, making it a candidate for further research and development in medicinal chemistry.
Used in Material Science:
5-(2,4-DICHLOROPHENYL)CYCLOHEXANE-1,3-DIONE has garnered interest in material science for its potential application in developing novel materials and polymers. Its distinctive chemical structure and reactivity offer opportunities for innovation in material design and engineering, potentially leading to advancements in various industries that rely on advanced materials.

InChI:InChI=1/C12H10Cl2O2/c13-8-1-2-11(12(14)5-8)7-3-9(15)6-10(16)4-7/h1-2,5,7H,3-4,6H2

Upstream product

• 66896-92-2 4-(2',4'-dichlorophenyl)-3-buten-2-one 
• 105-53-3 diethyl malonate 
• 66896-92-2 (E)-4-(2,4-dichlorophenyl)but-3-en-2-one 
• 874-42-0 2,4-dichlorobenzaldeyhde 

Downstream Products

• 91700-87-7 7-chloro-3-(2,4-dichlorophenyl)-1,2,3,4,9,10-hexahydroacridine-1,9-dione 
• 144155-24-8 6-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione 
• 144155-12-4 5,8-Dichloro-3-(2,4-dichloro-phenyl)-3,4-dihydro-2H,10H-acridine-1,9-dione 
• 55579-48-1 7-chloro-3-(2,4-dichlorophenyl)-10-hydroxy-1-oxo-1,2,3,4-tetrahydro-9 (10H)-acridone 
• 61888-44-6 3-Chloro-5-(2,4-dichloro-phenyl)-cyclohex-2-enone 
• 144155-65-7 1-[(E)-2-Amino-ethylimino]-7-chloro-3-(2,4-dichloro-phenyl)-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 144155-53-3 6-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-3-dimethylamino-propylimino]-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 80092-76-8 7-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-3-dimethylamino-propylimino]-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 80092-75-7 7-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-2-diethylamino-ethylimino]-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 144155-41-9 5-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-3-dimethylamino-propylimino]-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 144155-64-6 7-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-2-(2-hydroxy-ethylamino)-ethylimino]-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 80092-77-9 7-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-4-diethylamino-butylimino]-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 144155-58-8 7-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-3-pyrrolidin-1-yl-propylimino]-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 80092-57-5 7-Chloro-3-(2,4-dichloro-phenyl)-1-[(E)-3-dimethylamino-propylimino]-10-hydroxy-1,3,4,10-tetrahydro-2H-acridin-9-one 

Relevant academic research and scientific papers

SUBSTITUTED DIHYDROPYRIDINES AND METHODS OF USE

Compounds are provided that are modulators of the C5a receptor. The compounds are substituted dihydropyridines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activtation of C5a receptors.

Synthesis and Antimalarial Properties of 1-Imino Derivatives of 7-Chloro-3-substituted-3,4-dihydro-1,9(2H,10H)-acridinediones and Related Structures

To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and primates.Among structural modifications prepared, including N10-alkyl and C2-substituted analogs, removal of the C9 oxygen, and introduction of an imino side chain at C9, the imines of the N10-H acridinediones were the most active compounds obtained.The imino derivative of7-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione (9aa) proved to be highly active in advanced studies in primates.

7-Chloro-3-substituted aryl-3,4-dihydro-1,9(2H,10H) and 10 hydroxy acridinedioneimines having antimalarial activity

7-Chloro-3-substituted aryl-3,4-dihydro-1,9-(2H,1OH) and 10-hydroxy-acridinedioneimines and their pharmaceutically acceptable salts and a process for preparing them are disclosed and claimed. The compounds are useful in the treatment of protozoan diseases