55583-11-4

Upstream product

• 6626-15-9 4-Bromoresorcinol 
• 100-39-0 benzyl bromide 
• 3769-42-4 1,3-bis(benzyloxy)benzene 
• 108-46-3 recorcinol 

Downstream Products

• 70434-18-3 3-(2,4-dibenzyloxyphenyl)cyclohexanone 
• 284036-82-4 1,3-di-O-benzyl-4-(2,3,4,5-tetra-O-benzyl-D-allo/altro-pentit-1-yl)resorcinol 
• 198494-30-3 2,4-dibenzyloxyphenyl boronic acid 
• 862081-62-7 2-(2,4-dibenzyloxyphenyl)-6-methoxy-1-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-naphthalene 
• 1310406-75-7 tert-butyl 4-(2,4-bisbenzyloxyphenyl)-4-hydroxy-piperidine-1-carboxylate 
• 1310406-76-8 tert-butyl 4-(2,4-dihydroxyphenyl)piperidine-1-carboxylate 
• 1310406-77-9 4-(piperidin-4-yl)-benzene-1,3-diol hydrochloride 
• 1310406-58-6 4-(1-phenylmethanesulphonylpiperidin-4-yl)-benzene-1,3-diol 
• 1393115-25-7 (2,4-bis(benzyloxy)phenyl)(pyridin-2-yl)methanone 
• 1393115-26-8 1-(2,4-bis(benzyloxy)phenyl)-1-(pyridin-2-yl)ethanol 
• 1393115-08-6 4-(1-(pyridin-2-yl)ethyl)benzene-1,3-diol 
• 1393115-09-7 4-(1-(pyridin-3-yl)ethyl)benzene-1,3-diol 
• 1393115-24-6 (2,4-bis(benzyloxy)phenyl)(pyridin-2-yl)methanol 
• 1393115-27-9 1-(2,4-bis(benzyloxy)phenyl)-1-(pyridin-3-yl)ethanol 

Relevant academic research and scientific papers

Synthesis of 2,6,9-substituted xanthen-3-one and solvent effect on structural and photophysical properties

The synthesis of donor-π-donor type 2,6,9-substituted xanthen-3-one and its solvent effect on both the structural and photophysical properties were revealed. The keto-enol isomerization behavior and red-shift of the emission wavelengths were observed depe

Facile and divergent optimization of chromazonarol enabled the identification of simplified drimane meroterpenoids as novel pharmaceutical leads

The diversity of drimane hydroquinones was significantly expanded by the facile construction of (+)-chromazonarol relevant natural products, isomers, and analogues for the discovery of new pharmaceutical leads. The structure-activity relationship of (+)-c

Process Development and Good Manufacturing Practice Production of a Tyrosinase Inhibitor via Titanium-Mediated Coupling between Unprotected Resorcinols and Ketones

A concise and economically attractive process for the synthesis of a novel tyrosinase inhibitor has been developed and implemented on a multikilogram scale under GMP. A major achievement to the success of the process is the development of a direct coupling between free resorcinol and ketone. First developed under basic conditions, this coupling has been turned to a novel titanium(IV) mediated process allowing good selectivity, easy isolation, and high atom efficiency. Other key steps feature an alkene reduction by palladium catalyzed transfer hydrogenation and a urea formation using N,N′-disuccinimidyl carbonate as the carbonyl source. This route allowed us to produce kilogram batches of the candidate to support preclinical and clinical studies.

A solution for detecting metal ion content of organic compound and use thereof

The invention relates to organic compounds used for detecting metal ion contents in solutions. The organic compounds can be used for biomedicine, environment monitoring, and the like. By introduction of color developing groups or fluorophores into ortho p

Enantioselective synthesis, stereochemical correction, and biological investigation of the rodgersinine family of 1,4-benzodioxane neolignans

The enantioselective synthesis and chiroptic analysis of all members of the rodgersinine family of 1,4-benzodioxane neolignans has been achieved. ECD spectra and optical rotation analysis determined that the previously published stereochemistry of trans-rodgersinines A and B was incorrect. The cis-rodgersinines A and B did not follow the model ECD study commonly used to assign the absolute stereochemistry of 1,4-benzodioxane natural products. This finding has implications on the absolute stereochemistry of other natural products of this type. Additionally, the rodgersinines were found to have anti-HCV activities.

HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF

The invention relates to a compound of general formula (I) characterized in that: R1 is a C1-C4 alkyl group, andR2 is an optionally substituted nitrogen, sulfur or oxygen containing heteroaromatic ring.

AROMATIC RING COMPOUND

Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity, and is useful as an agent for the prophylaxis or treatment of diabetes and the like.

Formal synthesis of soybean phytoalexin glyceollin i

Glyceollins are well-known phytoalexins isolated from soybean (Glycine max). An efficient three-step synthesis was developed for the preparation of the key intermediate in Khupse's glyceollin I synthesis. Claisen rearrangement-cyclization cascade reaction

4- (AZACYCLOALKYL) -BENZENE-1, 3 -DIOL DERIVATIVES AS TYROSINASE INHIBITORS AND THEIR SYNTHESIS AND USE THEREOF

The present invention concerns novel 4-(azacycloalkyl)-benzene-1,3-diol compounds with the following general formula (I): to compositions containing them, to a process for their preparation and to their use in pharmaceutical or cosmetic compositions for t

NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS

The present invention relates to novel 4- (azacycloalkyl) benzene-1, 3-diol compounds corresponding to general formula (I) below: Formula (I) to the compositions containing same, to the process for the preparation thereof and to the use thereof in pharmaceutical or cosmetic compositions for use in the treatment or prevention of pigmentary disorders.