55611-45-5

Upstream product

• 62134-69-4 N-(2-methyl-2-propen-1-ylidene)cyclohexylamine 
• 62134-57-0 [2-Chloro-2-methyl-prop-(E)-ylidene]-cyclohexyl-amine 
• 108-91-8 cyclohexylamine 
• 563-47-3 3-Chloro-2-methylpropene 

Downstream Products

• 25675-95-0 Cyclohexyl-(2-methyl-allyl)-dithiocarbamic acid 2,4-dinitro-phenyl ester 
• 67189-65-5 Cyclohexyl-(2-methyl-allyl)-thiocarbamic acid S-ethyl ester 
• 62371-16-8 N-Cyclohexyl-N-methallylthiocarbamidsaeure-O-ethylester 
• 67189-69-9 Cyclohexyl-(2-methyl-allyl)-thiocarbamic acid O-phenyl ester 
• 134638-01-0 1-Cyclohexyl-1,3-bis-(2-methyl-allyl)-thiourea 
• 124016-16-6 N-cyclohexyl-4-methyl-3-pyrrolin-2-one 
• 1048691-69-5 3-chloro-4,4-dimethyl-1-cyclohexylpyrrolidin-2-one 
• 55611-44-4 N⁶-cyclohexyl-N⁶-(2-methyl-allyl)-adenosine 
• 96240-05-0 N-Cyclohexyl-4-methyl-2-pyrrolidone 
• 66128-31-2 6-chloromethyl-4-cyclohexyl-6-methyl-[1,2,4]dithiazinan-3-one 

Relevant academic research and scientific papers

DIRECT REGIO- AND STEREO-SELECTIVE LITHIATION OF SECONDARY ALLYL AND METHYLALLYL AMINES: A NEW TYPE OF γ-AMINATED ORGANOLITHIUM REAGENTS IN ORGANIC SYNTHESIS

Several secondary allyl and methylallylamines (6) have been regio- and stereo-selectively lithiated with t-butyl-lithium, giving the corresponding sp2 γ-aminated organolithium intermediates (7), which by reaction with electrophiles D2O, Me2S2,

Synthesis of Secondary Allylic Amines

Secondary allylic amines were synthesized from aldehydes and primary amines via successive conversion into aldimines, α-haloaldimines and α,β-unsaturated aldimines, the latter being selectively reduced by sodium borohydride at the imino function.This method allowed the synthesis of secondary allylic amines with high preponderance of the E-stereochemistry.A comparison was made with an alternative method involving the generation of α,β-unsaturated aldimines from α,β-unsaturated aldehydes and primary amines, and subsequent borohydride reduction.