556113-62-3 Usage
General Description
The chemical "(2R)-4-[5-Chloro-2-[(4-methoxyphenyl)thio]phenyl]-2-methyl-1-piperazineacetic acid" is a complex organic compound with a molecular formula and structure that includes a piperazine ring, a chloro-substituted thiophenyl group, a methoxyphenyl group, and an acetic acid moiety. (2R)-4-[5-Chloro-2-[(4-methoxyphenyl)thio]phenyl]-2-methyl-1-piperazineacetic acid is a piperazine derivative, which is a class of compounds known for their pharmacological properties, including their ability to act as central nervous system stimulants and therapeutic agents for various medical conditions. The specific pharmacological effects of "(2R)-4-[5-Chloro-2-[(4-methoxyphenyl)thio]phenyl]-2-methyl-1-piperazineacetic acid" are not readily apparent from its chemical structure alone, and further research and testing would be needed to determine its potential applications in medicine or other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 556113-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,6,1,1 and 3 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 556113-62:
(8*5)+(7*5)+(6*6)+(5*1)+(4*1)+(3*3)+(2*6)+(1*2)=143
143 % 10 = 3
So 556113-62-3 is a valid CAS Registry Number.
556113-62-3Relevant articles and documents
The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors
Smith, Garrick,Ruhland, Thomas,Mikkelsen, Gitte,Andersen, Kim,Christoffersen, Claus Tornby,Alifrangis, Lene Hjorth,Mork, Arne,Wren, Stephen P.,Harris, Neil,Wyman, Barry M.,Brandt, Guillaume
, p. 4027 - 4030 (2007/10/03)
Elevation of glycine levels and activation of the NMDA receptor by inhibition of the glycine transporter 1 (GlyT-1) is a potential strategy for the treatment of schizophrenia. A novel series of GlyT-1 inhibitors have been identified containing the 2-arylsulfanyl-phenylpiperazine motif. The most prominent member of this series, (R)-4-[5-chloro-2-(4-methoxy-phenylsulfanyl)- phenyl]-2-methyl-piperazin-1-yl-acetic acid (31) is a potent glycine transporter-1 inhibitor (IC50=150nM), which elevated glycine levels in rat ventral hippocampus as measured by microdialysis in vivo at doses of 1.2-4.6mg/kg s.c.
