55622-00-9Relevant academic research and scientific papers
Studies with 3-substituted 2-arylhydrazono-3-oxoaldehydes: New routes for synthesis of 2-arylhydrazono-3-oxonitriles, 4-unsubstituted 3,5-diacylpyrazoles and 4-arylazophenols
Al-Saleh, Balkis,El-Apasery, Morsy A.,Elnagdi, Mohamed Hilmy
, p. 578 - 580 (2007/10/03)
Compounds 1a-c reacts with hydroxylamine-O-sulfonic acid or with hydroxylamine hydrochloride in aqueous acetic acid in the presence of sodium acetate to yield the 3-oxoalkanonitriles 3, which were converted into arylazoisoxazole and 1,2,4-triazine derivatives 10. The hydrazones 1a-c reacted with chloroacetone or with phenacyl bromide in refluxing ethanol and in presence of K2CO3 to yield the pyrazoles 12a-e, formed most likely via intermediately formed 11a-e. The reaction of 1a,b with acetone afforded the arylazophenols.
