60083-18-3

Basic information

• Product Name: 3-OXO-3-PHENYL-2-(2-PHENYLHYDRAZONO)PROPANAL
• Synonyms: 3-OXO-3-PHENYL-2-(2-PHENYLHYDRAZONO)PROPANAL;(2E)-3-oxo-3-phenyl-2-(2-phenylhydrazin-1-ylidene)propanal
• CAS NO: 60083-18-3
• Molecular Formula: C₁₅H₁₂N₂O₂
• Molecular Weight: 252.27
• Mol File: 60083-18-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-OXO-3-PHENYL-2-(2-PHENYLHYDRAZONO)PROPANAL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-OXO-3-PHENYL-2-(2-PHENYLHYDRAZONO)PROPANAL(60083-18-3)
• EPA Substance Registry System: 3-OXO-3-PHENYL-2-(2-PHENYLHYDRAZONO)PROPANAL(60083-18-3)

Safety Data

• Hazardous Substances Data: 60083-18-3(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 1131-80-2 (E)-3-(N,N-dimethylamino)-1-phenyl-2-propen-1-one 
• 100-34-5 benzene diazonium chloride 

Downstream Products

• 1055324-54-3 1-[6-benzoyl-2-phenyl-2,3-dihydropyridazin-4-yl]ethanone 
• 1055324-46-3 6-benzoyl-2-phenyl-2,3-dihydropyridazine-4-carbonitrile 
• 60083-28-5 3-oxo-3-phenyl-2-(phenylhydrazono)propanal 
• 135659-90-4 phenyl 3-(1-phenylpyrazolyl) ketone 
• 3313-16-4 (1RS,2SR)-2-benzoylamino-1,3-bis-benzoyloxy-1-phenyl-propane 
• 50610-93-0 (1RS,2SR)-2-benzoylamino-1-phenyl-propane-1,3-diol 
• 55622-00-9 5-phenyl-4-(phenylazo)-isoxazol-3-ylamine 
• 849820-89-9 (5-benzoyl-1-phenyl-1H-pyrazol-3-yl)-phenylmethanone 
• 936132-85-3 (E)-2-oxo-N′,2-diphenylacetohydrazonoyl cyanide 

Relevant articles and documents

Arylhydrazonals as the aldehyde component in Baylis-Hillman reactions

Arylhydrazonals were added to acrylonitrile or methyl vinyl ketone in the presence of DABCO or benzotriazole to yield the intermediate Baylis-Hillman adduct that cyclized under the reaction conditions with water elimination to yield dihydropyridazines. A pyridazine reacted with DMAD to yield a pyridine via a [4+2] Diels-Alder addition followed by retro Diels-Alder elimination of methylene aniline. Two pyridazines were condensed with DMFDMA to yield the corresponding enaminones that reacted with NH2NH2 to afford the pyrazolylpyridazines.

Studies with functionally substituted heteroaromatics: A novel route for the synthesis of 1-aryl-6-oxopyridazinones, 1-arylpyridazine-6-imines and 1-aryl-6-imino-4-pyridazinals

Aryldiazonium salts couple with the 3-dimethylamino-1-substituted enones 1 a-c to yield 2-arylhydrazono-3-oxo-3-substituted-propanals which are excellent precursors for the synthesis of pyridazinones. The coupling reaction of 2-cyano-5-dimethylamino-3-substituted-penta-2,4-dienonitrile 12 a-b with benzene diazonium salts in ethanolic sodium hydroxide gives the pyridazinals 13a,b.