55645-40-4

Usage

Uses

Used in Organic Chemistry:
Erythro-N-benzyl-3-(benzylamino)aspartic acid is used as a building block in organic chemistry for the synthesis of complex organic molecules. Its unique structure and functional groups facilitate the creation of novel compounds with specific properties.
Used in Drug Development Research:
In the pharmaceutical industry, erythro-N-benzyl-3-(benzylamino)aspartic acid is employed as a key component in drug development research. Its distinct molecular structure and properties make it a valuable tool for the study and development of new therapeutic agents.
Used in Peptide Synthesis:
Erythro-N-benzyl-3-(benzylamino)aspartic acid is used as a monomer in peptide synthesis, contributing to the formation of bioactive peptides with potential applications in medicine and biotechnology.
Used in Pharmaceutical Synthesis:
erythro-N-benzyl-3-(benzylamino)aspartic acid is utilized as a starting material or intermediate in the synthesis of pharmaceuticals, particularly those targeting specific biological pathways or receptors. Its unique structure allows for the development of drugs with improved efficacy and selectivity.

InChI:InChI=1/C18H20N2O4/c21-17(22)15(19-11-13-7-3-1-4-8-13)16(18(23)24)20-12-14-9-5-2-6-10-14/h1-10,15-16,19-20H,11-12H2,(H,21,22)(H,23,24)

Upstream product

• 608-36-6 meso-2,3-dibromosuccinic acid 
• 100-46-9 benzylamine 
• 7732-18-5 water 
• 64-17-5 ethanol 
• 526-78-3 2,3-dibromosuccinic acid 
• 67-66-3 chloroform 

Downstream Products

• 51591-75-4 cis-1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid 
• 23220-52-2 (2S,3R)-3-aminoaspartic acid 
• 921-52-8 racem.-2,3-diamino-succinic acid 
• 89535-38-6 (+/-)-1-benzyl-2-oxo-imidazolidine-4r,5c-dicarboxylic acid 
• 17128-89-1 meso-2,3-bis(benzylamino)-1,4-butanediol 

Relevant academic research and scientific papers

CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES

A novel cross-linked cytotoxic agents, pyrrolobenzo-diazepine dimer (PBD) derivatives, and their conjugates to a cell-binding molecule, a method for preparation of the conjugates and the therapeutic use of the conjugates.

CONJUGATION LINKERS CONTAINING 2,3-DIAMINOSUCCINYL GROUP

Provided is a conjugate of a cytotoxic drug/molecule to a cell-binding molecule with a bis-linker (adual-linker) containing a 2, 3-diaminosuccinyl group. It also relates to preparation of the conjugate of a cytotoxic drug/molecule to a cell-binding molecule with the bis-linker, particularly when the drug having functional groups of amino, hydroxyl, diamino, amino-hydroxyl, dihydroxyl, carboxyl, hydrazine, aldehyde and thiol for conjugation with the bis-linker in a specific manner, as well as the therapeutic use of the conjugates.

Method of treating DBA mother liquor

The present invention relates to a method of treating a DBA mother liquor, wherein a small amount of a reagent is used, high DBA yield is provided, and waste is less.

Oxidation of Alkenes and Sulfides with Transition Metal Catalysts

Alkenes and sulfides were oxidized with transition-metal catalysts.The oxidant sources include molecular dioxygen, air and iodosylbenzene.The metal ions Mn(III), Fe(III), Co(II) and Ni(II) were used.The catalysts 1-18 of 1,3-dioxo-, β-ketoimine- or salen-types were prepared and their efficacy was examined. 1,2-Dihydronaphthalene is most efficiently epoxidized with O2/Me2CHCHO or PhIO in the presence of Mn(III)-salen catalysts.The Ni(II)-, Co(II)- and Fe(III)-catalysts of either β-ketoimine- or salen-types are useful for epoxidation of styrene, (E)-stilbene and (E)-benzalacetone in the O2/Me2CHCHO system; these epoxidations are stereospecific without formation of corresponding diastereomeric epoxides.Oxidation of methyl p-totyl sulfide with O2/Me2CHCHO is facilitated by the 1,3-dioxo-catalyst Co(II)-1.Monooxidation is achieved with Me2CHCHO in equimolar proportions to give the corresponding sulfoxide, whereas overoxidation is realized with excess Me2CHCHO to give the sulfone.These epoxidation and sulfide oxidations all occur at 25 deg C and are complete in less than a day.Key Words: Oxidation; Transition metals; Alkenes; Sulfides; 1,3-Diketone; β-Ketoimine; Salen.