55654-19-8 Usage
General Description
2-Chloro-N-(3-cyano-thiophen-2-yl)-acetamide is a chemical compound with the molecular formula C8H6ClN3OS. It is a yellowish solid with a molecular weight of 221.67 g/mol. 2-CHLORO-N-(3-CYANO-THIOPHEN-2-YL)-ACETAMIDE is commonly used in organic synthesis and chemical research as a reagent or intermediate. It contains a chloro group, a cyano group, and a thiophene ring, making it useful in the creation of pharmaceuticals, agricultural chemicals, and materials science. Additionally, the presence of the acetamide group gives it potential as a building block in the synthesis of various organic compounds. The exact properties and uses of this chemical compound may vary depending on the specific application and reaction conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 55654-19-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,6,5 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 55654-19:
(7*5)+(6*5)+(5*6)+(4*5)+(3*4)+(2*1)+(1*9)=138
138 % 10 = 8
So 55654-19-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClN2OS/c8-3-6(11)10-7-5(4-9)1-2-12-7/h1-2H,3H2,(H,10,11)
55654-19-8Relevant articles and documents
Synthesis of Hetaryl Pyridinium Salts and Fused 3-Amino-pyrid-2-ones
Rehwald, Matthias,Bellmann, Peter,Jeschke, Torsten,Gewald, Karl
, p. 371 - 378 (2007/10/03)
1-(3-Coumaryl)-pyridinium salts 3 and 1-(3-coumaryl)-tetrahydrothiophenium salts 5 were synthesized from 2-acylphenyl chloro- or bromoacetates 2. 2-Chloro-N1-(3,4-dimethoxyphenyl)-acetamide and substituted 2-chloro-N1-(2-thienyl)-acetamides 8 react with acetyl chloride and pyridine to yield the quinolinyl- and (thieno[2,3-b]pyridin-5-yl)-pyridinium salts 10. Fused thieno[2,3-b]pyridin-ones 19 were formed from N-chloroacetyl-2-aminothiophen-3-carbonitriles 16 with pyridine via Thorpe-Ziegler cyclization and followed by cyclodehydrogenation. In presence of pyridine alkyl 2-chloro-acetylaminobenzoates 21 yield 3-(1-pyridinio)-quinoline-4-olates 23. Zincke-cleavage of 10 and 23 with hydrazinium hydroxide leads to fused 3-amino-pyridine-2-ones 11 and 3-amino-4-hydroxy-quinoline-2-ones 24, respectively. Oxazoloquinolines 25 were synthesized from 24 with acetic anhydride.
