55692-30-3Relevant academic research and scientific papers
PYRAZOLOTHIAZOLE COMPOUND AND MEDICINE
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Paragraph 0143, (2017/07/31)
The invention provides a pyrazolothiazole compound of the formula [I], or a pharmaceutically acceptable salt thereof: The compound of the invention has JAK1 inhibitory activity, and thus, immunosuppressive effect, anti-inflammatory effect and anti-proliferative effect, and is useful in the treatment of the diseases, for example, rheumatoid arthritis, inflammatory bowel disease, psoriasis and vasculitis, bronchial asthma, chronic obstructive pulmonary disease and eosinophilic sinusitis, nasal polyp.
AROMATIC COMPOUND
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Paragraph 0823; 0824; 1103; 1104, (2016/05/19)
Provided is a novel aromatic ring compound having a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula: wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity and a GLP-1 secretagogue action, is useful for the prophylaxis or treatment of cancer, obesity, diabetes, hypertension, hyperlipidemia, cardiac failure, diabetic complications, metabolic syndrome, sarcopenia and the like, and affords superior efficacy.
N-(1-(ω-phenyl-alkyl)-piperidyl-4)-N-(α-pyridyl)-carboxylic acid amides and salts thereof
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, (2008/06/13)
Compounds of the formula SPC1 Wherein R is straight or branched alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 2 carbon atoms or phenyl, and n is an integer from 2 to 4, inclusive, And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as non-narcotic analgesics.
