55692-31-4

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
Piperidin-4-yl-pyridin-2-yl-amine is utilized as a key intermediate in the synthesis of various pharmaceutical agents due to its potential therapeutic applications across different medical conditions.
Used in Cancer Treatment:
In the field of oncology, Piperidin-4-yl-pyridin-2-yl-amine is employed as a prospective anti-cancer agent, targeting a range of malignancies. Its structure allows for interactions with cellular targets, potentially leading to the inhibition of cancer cell growth and proliferation.
Used in Neurological and Psychiatric Treatments:
Piperidin-4-yl-pyridin-2-yl-amine is also being investigated for its potential to treat neurological disorders and psychiatric conditions, capitalizing on its ability to modulate neurotransmitter systems and influence neuronal function.
Used in Development of Novel Medications:
Beyond its direct applications, Piperidin-4-yl-pyridin-2-yl-amine serves as a building block in the creation of new drugs for a variety of medical conditions, highlighting its versatility in medicinal chemistry.

InChI:InChI=1/C10H15N3/c1-2-6-12-10(3-1)13-9-4-7-11-8-5-9/h1-3,6,9,11H,4-5,7-8H2,(H,12,13)

Upstream product

• 67-63-0 isopropyl alcohol 
• 63260-55-9 ethyl 4-(2-pyridinylamino)-1-piperidinecarboxylate 
• 372-48-5 2-fluoropyridine 
• 55692-30-3 N-(1-benzylpiperidin-4-yl)pyridin-2-amine 
• 50541-93-0 4-amino-1-benzylpiperidine 

Downstream Products

• 445378-16-5 N-{2-[2-(4-cyanophenyl)-ethyl]-1-methyl-benzimidazol-5-yl}-N-(4-tert-butylphenylmethyl)-2-[4-(2-pyridylamino)-piperid-1-yl]-acetamide 

Relevant academic research and scientific papers

PYRAZOLOTHIAZOLE COMPOUND AND MEDICINE

The invention provides a pyrazolothiazole compound of the formula [I], or a pharmaceutically acceptable salt thereof: The compound of the invention has JAK1 inhibitory activity, and thus, immunosuppressive effect, anti-inflammatory effect and anti-proliferative effect, and is useful in the treatment of the diseases, for example, rheumatoid arthritis, inflammatory bowel disease, psoriasis and vasculitis, bronchial asthma, chronic obstructive pulmonary disease and eosinophilic sinusitis, nasal polyp.

NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS

A subject of the invention is the compounds of formula (I): in which either R1 represents H, OH, NH2, —(CH2)m—NRaRb(m=0.1 or 2),Ra and Rb represent H, linear, branched or cyclic (C1 -C6) alkyl, (C3-C6) cycloalkyl-(C3-C6)— alkyl, Rc, S(O)2Rc, C(O)Rc, S(O)2Rd or C(O)Rd;or Ra and Rb with N form an Rc radical;Rc represents a saturated, unsaturated or 5- or 6-members aromatic ring, containing 1 to 4 heteroatoms chosen from N, O and S, optionally substituted;Rd represents a linear, branched or cyclic (C1-C6) alkyl, optionally substituted by 1 to 4 halogens;or R1 represents Rc or CHReRc or CHReRd;Re represents H, OH, NH2, NH—(C1-C6)-alk or N-(C1-C6)-alk2, or NH—(C1-C7)-acyl or NHRc;R2 represents H, (CH2)m—NRaRb, Rc, CHReRc or CHReRd, and R′2 represents H; it being understood that R1 and R2 cannot at the same time be H or that R1 and R2 or R2 and R1 cannot be one (CH2)m—NRaRb or Rc or H and the other one OH, or one H and the other one NH2, or one H and the other one (CH2)m—NRaRb in which Ra and Rb represent H or alkyl or C(O)Rd, in which Rd represents an unsubstituted alkyl or cycloalkyl; or R1 has the above definition except H and R2 and R′2 together represent gem dialkyl or alkyl-oxime, or R2 and R′2 represent respectively Rc or Rd and OH, NH2, NHRc or NHRf, Rf being a (C1-C7) acyl radical;or R1 represents H and R2 and R′2 together represent alkyl-oxime or one represents Rc and the other one represents OH, NH2, NHRc or NHRf;n is 0 or 1;R3 and R′3 represent H or (C1-C6) alkyl optionally substituted by 1 to 3 halogens or R3 represents (C1-C6) alkoxy carbonyl and R′3 represents H;R4 represents methyl optionally substituted by halogen;R5 represents H, (C1-C6) alkyl or (C7-C12) arylalkyl;R6 represents H, fluorine, NO2, CF3 or CN;in the form of enantiomers or mixtures, as well as their salts with acids and bases; their preparation and their application as anti-bacterials, in both human and veterinary medicine.

N-Aryl-N-(1-L-4-piperidinyl)-arylacetamides

Novel N-aryl-N-(1-L-4-piperidinyl)arylacetamides useful as anti-arrhythmic agents, a method of treating arrhythmia which comprises the systemic administration of such compounds to warm-blooded animals and pharmaceutical compositions to be used therefor.

N-aryl-N-(1-alkyl-4-piperidinyl)-arylacetamides

Novel N-aryl-N-(1-L-4-piperidinyl)arylacetamides useful as antiarrhythmic agents, a method of treating arrhythmia which comprises the systemic administration of such compounds to warm-blooded animals and pharmaceutical compositions to be used therefor.

N-(1-(ω-phenyl-alkyl)-piperidyl-4)-N-(α-pyridyl)-carboxylic acid amides and salts thereof

Compounds of the formula SPC1 Wherein R is straight or branched alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 2 carbon atoms or phenyl, and n is an integer from 2 to 4, inclusive, And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as non-narcotic analgesics.