55744-85-9

Upstream product

• 10435-55-9 4-ethoxy-2-hydroxybenzoic acid 
• 77-78-1 dimethyl sulfate 
• 64-67-5 diethyl sulfate 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 102232-45-1 methyl 4-ethoxy-2-hydroxybenzoate 
• 2150-47-2 methyl 2,4-dihydroxybenzoate 

Downstream Products

• 141180-71-4 1-[1-(2-methoxy-4-ethoxybenzoyl)-4-piperidinyl]-3,4-dihydrothiocarbostyril 
• 195507-73-4 4-Ethoxy-2-methoxybenzoyl chloride 

Relevant academic research and scientific papers

Rational Design of Rod-Like Liquid Crystals Exhibiting Two Nematic Phases

Recently, a polar, rod-like liquid-crystalline material was reported to exhibit two distinct nematic mesophases (termed N and NX) separated by a weakly first-order transition. Herein, we present our initial studies into the structure–property relationships that underpin the occurrence of the lower-temperature nematic phase, and report several new materials that exhibit this same transformation. We have prepared material with significantly enhanced temperature ranges, allowing us to perform a detailed study of both the upper- and lower-temperature nematic phases by using small-angle X-ray scattering. We observed a continuous change in d spacing rather than a sharp change at the phase transition, a result consistent with a transition between two nematic phases, structures of which are presumably degenerate.

Fluorescent photoremovable precursor (acridin-9-ylmethyl)ester: Synthesis, photophysical, photochemical and biological applications

A series of carboxylic acids including amino acids were protected as their corresponding fluorescent ester conjugates by coupling with an environment sensitive fluorophore 9-methylacridine. Photophysical properties of all the ester conjugates along with the protecting group have been investigated. Interestingly, the emission properties of the ester conjugates and 9-methylacridine were found to be highly sensitive to polarity, H-bonding and pH of the environment. Photolysis of all the ester conjugates was carried out using UV light above 360 nm and it was found that in every case the corresponding carboxylic acids were released in high chemical yield. Further, intercalation and the preferred binding mode of acridine-9-methanol and its ester conjugates with DNA were studied. In vitro biological studies revealed that acridine-9-methanol has good biocompatibility, cellular uptake property and cell imaging ability. The Royal Society of Chemistry and Owner Societies 2013.