557794-38-4

Usage

Uses

Used in Pharmaceutical Research:
Dapsone-D8 (major) is used as a research compound for studying the pharmacokinetics, metabolism, and mechanism of action of Dapsone. The presence of deuterium atoms in the molecule allows for better understanding of its behavior in biological systems and can help in the development of more effective drugs.
Used in Drug Metabolism Studies:
Dapsone-D8 (major) is used as a metabolic tracer to investigate the metabolic pathways and enzyme interactions of Dapsone in the body. This information can be crucial for optimizing drug dosages and understanding potential drug-drug interactions.
Used in Chemical Synthesis:
Dapsone-D8 (major) can be used as a starting material or intermediate in the synthesis of other deuterated compounds. The presence of deuterium atoms can affect the reactivity and stability of the molecule, making it a valuable tool in the development of new chemical entities.
Used in Analytical Chemistry:
Dapsone-D8 (major) can be employed as an internal standard in analytical techniques such as mass spectrometry and gas chromatography. The presence of deuterium atoms provides a distinct mass signature, allowing for accurate quantification and identification of the compound in complex mixtures.
Used in Environmental Studies:
Dapsone-D8 (major) can be utilized as a tracer compound in environmental research to study the fate and transport of Dapsone in the environment. This information can help in understanding the potential environmental impact of Dapsone and inform strategies for its safe use and disposal.
Used in Material Science:
Dapsone-D8 (major) may have potential applications in material science, where the incorporation of deuterium atoms can influence the physical and chemical properties of materials. This can lead to the development of new materials with improved performance characteristics.

Upstream product

• 80-08-0 dapsone 
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• 15826-91-2 acetanilide-d5 
• 4165-61-1 aniline-d5 
• 557794-37-3 C₁₆H₈⁽²⁾H₈N₂O₄S 

Relevant academic research and scientific papers

A stable isotope labeling dapsone synthetic method

The invention relates to a synthetic method of stable isotope labeled aminophenylsulfone. The method comprises the following steps: by taking stable isotope labeled p-nitro halogeno benzene as a raw material, carrying out nucleophilic substitution to generate stable isotope labeled 4, 4'-dinitro phenyl sulfide; oxidizing to obtain stable isotope labeled 4, 4'-dinitro diphenyl sulfone; and finally carrying out reaction with a reducing agent to obtain the stable isotope labeled aminophenylsulfone. Compared with the prior art, according to the stable isotope labeled aminophenylsulfone prepared by the invention simply separated and purified, the chemical purity reaches over 99% and the isotope abundance is 99%, so that the demand of aminophenylsulfone detection of forbidden sulfonamides in the field of food safety can be fully satisfied.

Phenylene ring motions in isomeric glassy epoxy networks and their contributions to thermal and mechanical properties

Cross-linked epoxies prepared from diglycidyl ether of bisphenol A (DGEBA) exhibit substantial property differences due to isomeric structures of the diamine curatives, 3,3′- and 4,4′-diaminodiphenyl sulfone (DDS). Here, the motions of phenylene rings on both the bisphenol A (BPA) and DDS structures of the networks were investigated through solid-state NMR 2H line shape analysis to trace the molecular origins. Ring deuterated monomers, namely, DGEBA-d8, 33DDS-d8, and 44DDS-d8, were synthesized, and four deuterated networks were prepared. The line shapes of the ring motions were interpreted using a motional model that described both ring π-flips and main-chain fluctuations. The contributions of different ring motions to mechanical relaxations are elucidated, and the molecular origins of property differences are identified.

Deuterated Polyimides and Derivatives Thereof

The object of the present invention is to provide a polyimide compound useful as a raw material of a polymer for an optical waveguide that has excellent transparency and heat resistance, low moisture absorption, a small optical transmission loss, a high r

Synthesis of deuterated 4, 4′-diaminodiphenylsulfone (Dapsone) and related analogs

A general scheme tor the synthesis ot 4,4′-diaminodiphenylsulfone-d5 (Dapsone) from aniline-d5 is described. The method may have general application and the preparation of the related analogs, 4,4′-dimethylaminodiphenyl sulfone from aniline-d5 and 4,4′-dimethoxydiphenyl sulfone from phenol-d5, is also described. Copyright