55814-34-1Relevant academic research and scientific papers
Transition metal free intramolecular selective oxidative C(sp3)-N coupling: Synthesis of N-aryl-isoindolinones from 2-alkylbenzamides
Verma, Ajay,Patel, Saket,Meenakshi,Kumar, Amit,Yadav, Abhimanyu,Kumar, Shailesh,Jana, Sadhan,Sharma, Shubham,Prasad, Ch. Durga,Kumar, Sangit
supporting information, p. 1371 - 1374 (2015/02/18)
A synthetic method has been developed for the preparation of biologically important isoindolinones including indoprofen and DWP205190 drugs from 2-alkylbenzamide substrates by transition metal-free intramolecular selective oxidative coupling of C(sp3)-H and N-H bonds utilizing iodine, potassium carbonate and di-tert-butyl peroxide in acetonitrile at 110-140 °C.
Identification of a potent and noncytotoxic inhibitor of melanin production
Hwang, Soonho,Choi, Sang Yoon,Lee, Jin Hee,Kim, Shinae,In, Jinkyung,Ha, Sang Keun,Lee, Eunjung,Kim, Tae-Yoon,Kim, Sun Yeou,Choi, Sun,Kim, Sanghee
experimental part, p. 5602 - 5609 (2010/09/14)
On the basis of a hit from random screening, biaryl amide derivatives were prepared in a combinatorial manner via parallel solution-phase synthesis, and their effects on melanocytes were investigated to discover new effective skin depigmenting agents. Amo
