55816-57-4Relevant articles and documents
SELECTIVE REDUCTION OF α-KETO ESTERS WITH ORGANOTIN HYDRIDES APPLICATION TO ASYMMETRIC SYNTHESES
Rahm, A.,Pereyre, M.
, p. 843 - 848 (2007/10/02)
Organotin hydrides selectively reduce the keto functional group in α-keto esters such as pyruvates or benzoylformates.Hydrostannation of (-)-menthyl benzoylformate with achiral reagents occurs with 5-20percent asymmetric induction while the reaction of (-)-2-butyldiphenyltin hydride with ethyl benzoylformate only proceeds with a very low optical yield.