558465-78-4

Upstream product

• 917-64-6 methyl magnesium iodide 
• 127793-62-8 4-((tert-butyldiphenylsilyl)oxy)butanal 
• 93547-88-7 t-butyl diphenylsilanol 
• 75-16-1 methylmagnesium bromide 
• 130372-07-5 4-(tret-butyldiphenylsilyloxy)butan-1-ol 
• 626-95-9 1,4-Pentanediol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 944382-83-6 2-[4-(tert-butyldiphenyl-silanyloxy)-1-methyl-butylsulfanyl]-benzothiazole 
• 1206532-00-4 C₂₁H₂₉IOSi 
• 131074-33-4 5-(tert-butyldiphenylsilyloxy)-2-methyl-2-(phenylsulfanyl)-pentanal 
• 921229-06-3 (1E)-1-(2-(7-iodo-4-methylhept-3-enyl)-4-methoxyphenyl)pent-1-en-4-yn-3-one 
• 921229-07-4 (1E)-1-(2-(7-iodo-4-methylhept-3-enyl)-4-methoxyphenyl)pent-1-en-4-yn-3-one 
• 921229-05-2 (1E)-1-(2-(7-chloro-4-methylhept-3-enyl)-4-methoxyphenyl)pent-1-en-4-yn-3-one 
• 921229-30-3 (1E)-1-(2-(7-chloro-4-methylhept-3-enyl)-4-methoxyphenyl)pent-1-en-4-yn-3-one 
• 921229-04-1 (1E)-1-(2-(7-chloro-4-methylhept-3-enyl)-4-methoxyphenyl)pent-1-en-4-yn-3-ol 
• 921229-27-8 (1E)-1-(2-(7-chloro-4-methylhept-3-enyl)-4-methoxyphenyl)pent-1-en-4-yn-3-ol 

Relevant academic research and scientific papers

Chemoselective deoxygenation of ether-substituted alcohols and carbonyl compounds by B(C6F5)3-catalyzed reduction with (HMe2SiCH2)2

B(C6F5)3-catalyzed deoxygenation of ether-substituted alcohols and carbonyl compounds has been developed using (HMe2SiCH2)2 as the reductant. This unique reagent shows distinct superiority over traditional one silicon-centered hydrosilanes, giving the corresponding alkanes in high yields with good tolerance of ethers, aryl halides and alkenes. The control experiments suggest that (HMe2SiCH2)2 might facilitate the approach in an intramolecular Si/O activation manner.

NOVEL PTEFB INHIBITING MACROCYCLIC COMPOUNDS

The present invention relates to novel modified macrocyclic compounds with improved tolerability of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in par

Synthetic studies toward neovibsanins A and B: construction of the neovibsanin core utilizing palladium(0)-catalyzed carbonylative cyclization with carbon monoxide

The core A-ring of neovibsanins A (1) and B (2), which are potent neurotrophic agents isolated from the leaves of Viburnum awabuki, have been effectively constructed by the intramolecular palladium(0)-catalyzed carbonylative cyclization of alkenyl iodide

Cascade radical-mediated cyclisations with conjugated ynone electrophores. An approach to the synthesis of steroids and other novel ring-fused polycyclic carbocycles

A cascade radical-mediated Diels-Alder reaction with the iododienynone 16b produced the tricyclic ketone 17 (22%). By contrast, treatment of the substituted furans 36 and 47 with Bu3SnH-AIBN, instead led to the tetracycles 44 and 58 respectivel

BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS

Provided are novel compounds having an inhibitory activity against production or secretion of β-amyloid protein. They embrace compounds represented by the following formula (1): and capable of being replaced with a variety of substituents; and salts thereof, and solvates of any one of them.

The scope and limitation of the [1,4]-SPh shift in the synthesis of allylic alcohols

Treatment of a series of 4-phenylsulfanyl-1,3-diols with toluene-p-sulfonyl chloride in pyridine gives stereospecifically substituted allylic alcohols in near quantitative yield via a [1,4]-SPh shift. We comment on the structural variation at both the mig