558644-64-7 Usage
Chemical class
Pyrazole
Contains a pyrazole ring
Has iodine, chlorine, methyl, and phenyl groups attached
Potential applications
Pharmaceutical, agrochemical, and materials science industries
Can be used as a building block in the synthesis of various organic compounds
Has potential for use as a research tool in the study of biological systems and chemical reactions
May have medicinal properties and could be investigated for its potential as a drug candidate in the future
Versatile and valuable chemical compound with a wide range of potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 558644-64-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,8,6,4 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 558644-64:
(8*5)+(7*5)+(6*8)+(5*6)+(4*4)+(3*4)+(2*6)+(1*4)=197
197 % 10 = 7
So 558644-64-7 is a valid CAS Registry Number.
558644-64-7Relevant academic research and scientific papers
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
Cheung, Kwai-Ming J.,Matthews, Thomas P.,James, Karen,Rowlands, Martin G.,Boxall, Katherine J.,Sharp, Swee Y.,Maloney, Alison,Roe, S. Mark,Prodromou, Chrisostomos,Pearl, Laurence H.,Aherne, G. Wynne,McDonald, Edward,Workman, Paul
, p. 3338 - 3343 (2007/10/03)
High-throughput screening identified the 3,4-diarylpyrazole CCT018159 as a novel and potent (7.1 μM) inhibitor of Hsp90 ATPase activity. Here, we describe the synthesis of CCT018159 and a number of close analogues together with data on their biochemical p