55873-31-9

Upstream product

• 50390-51-7 4'-methylisobutyrophenone 
• 55873-29-5 2,2-Dimethyl-1-p-tolylpentan-1-thion 
• 55873-28-4 2,2-Dimethyl-1-p-tolylpentan-1-on 
• 104-81-4 4-Methylbenzyl bromide 
• 70855-13-9 1-(4-methylphenyl)-hexane-2,5-dione 
• 70855-12-8 2-Methyl-5-<(4-methylphenyl)methyl>furan 
• 119927-15-0 3,3-Dimethyl-2-p-tolyl-hexanedioic acid dimethyl ester 
• 119927-14-9 (4,4-Dimethyl-3-p-tolyl-cyclohex-1-enyloxy)-trimethyl-silane 
• 119927-13-8 4,4-Dimethyl-3-p-tolyl-cyclohexanone 
• 55873-30-8 5,5-dimethyl-1-p-tolylcyclopentene 
• 119927-16-1 4,4-Dimethyl-2-oxo-3-p-tolyl-cyclopentanecarboxylic acid methyl ester 
• 70855-14-0 3-methyl-2-(4-methylphenyl)-2-cyclopenten-1-one 
• 15681-48-8 lithium dimethylcuprate 

Downstream Products

• 55873-32-0 5-cuparenone 

Relevant academic research and scientific papers

AN EFFICIENT SYNTHESIS OF (+/-)-CUPARENE FROM 4,4-Dimethyl-2-CYCLOHEXEN-1-ONE

An efficient synthesis of (+/-)-cuparene 1 from 4,4-dimethyl-2-cyclohexen-1-one 2 involves 1,4-addition by use of organozinc reagent, ozonolysis and Dieckmann condensation as the key steps.

A Simple and Efficient Total Synthesis of the Sesquiterpenes Cuparene and Iso-α-curcumene, from Furan Derivatives

3,3-Dimethyl-2-p-tolylcyclopentanone (7) was synthesised by 1,4-addition of lithium dimethylcuprate to 3-methyl-2-p-tolylcyclopentenone (6), which was derived from 5-methyl-2-(4-methylbenzyl)furan (4) through the diketone (5).Starting from the same intermediate (5), 2-p-tolylheptan-6-one (16) was also synthesised.These results constitute formal total syntheses of cuparene (9) and iso-α-curcumene (17) respectively.