50390-51-7

Basic information

• Product Name: 2,4'-dimethylpropiophenone
• Synonyms: 2,4'-dimethylpropiophenone;2-Methyl-1-p-tolyl-propan-1-one;2-methyl-1-(4-methylphenyl)propan-1-one
• CAS NO: 50390-51-7
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.22826
• EINECS: 256-572-9
• Mol File: 50390-51-7.mol
• Article Data: 54

Chemical Properties

• Melting Point: 235-236 °C
• Boiling Point: 242.1 °C at 760 mmHg
• Flash Point: 94.3 °
• Appearance: /
• Density: 0.95 g/cm³
• CAS DataBase Reference: 2,4'-dimethylpropiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4'-dimethylpropiophenone(50390-51-7)
• EPA Substance Registry System: 2,4'-dimethylpropiophenone(50390-51-7)

Safety Data

• Hazardous Substances Data: 50390-51-7(Hazardous Substances Data)

Usage

General Description

2,4'-dimethylpropiophenone, also known as 2,4'-DMPP, is an organic chemical compound with the formula C11H14O. It is a fragrance ingredient and is commonly used in the production of perfumes and flavoring agents. 2,4'-dimethylpropiophenone has a sweet, floral, and honey-like odor and is often used to enhance the aroma of various consumer products. It is also used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Additionally, 2,4'-dimethylpropiophenone is considered to be relatively stable and is not easily flammable, making it a versatile and valuable chemical in various industries.

Upstream product

• 5337-93-9 4'-methylpropiophenone 
• 77-78-1 dimethyl sulfate 
• 79-30-1 isobutyryl chloride 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 920-39-8 isopropylmagnesium bromide 
• 104-85-8 para-methylbenzonitrile 
• 14289-68-0 2-bromo-2-methyl-1-(4-methylphenyl)-1-propanone 
• 99-94-5 p-Toluic acid 
• 79-31-2 isobutyric Acid 
• 18228-44-9 2-methyl-1-(p-tolyl)propan-1-ol 
• 1068-55-9 isopropylmagnesium chloride 
• 874-60-2 4-methyl-benzoyl chloride 
• 7163-50-0 (4-methylphenyl)(oxo)acetic acid 
• 78-84-2 isobutyraldehyde 

Downstream Products

• 70922-78-0 2,2-dimethyl-4-morpholin-4-yl-1-p-tolyl-butan-1-one 
• 116470-50-9 1-Isopropyl-1-p-tolylallyl alcohol 
• 133283-75-7 2,2-dimethyl-1-(4-methylphenyl)-pent-4-en-1-one 
• 27228-55-3 α-Isopropyl-p-methylbenzylidenmalonsaeure-dinitril 
• 67-66-3 chloroform 
• 100-21-0 terephthalic acid 
• 64-19-7 acetic acid 
• 92250-34-5 4,4-dimethyl-5-oxo-5-p-tolyl-pentane nitrile 
• 142874-62-2 2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran 
• 274907-44-7 (+)-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine 
• 142874-71-3 2,2,4,6,7-Pentamethyl-3-(4-methylphenyl)-5-nitro-2,3-dihydrobenzofuran 
• 126275-12-5 4-methyl-3-p-tolyl-pent-2-enoic acid ethyl ester 
• 1364859-23-3 1-methyl-4-(3-methylbutan-2-yl)benzene 
• 22040-31-9 p-(1,2-dimethylpropyl)toluene 

Relevant articles and documents

Synthesis of novel chiral heterometallic terpene oximates: Unusual generation of an aluminium enolate by a cooperative effect

Al-K heterometallic terpene oximate derivatives with uncommon structural features are reported. These species react with an aryl ketone leading to heterometallic enolates via an unusual route. Isolation of a remarkable heterometallic Al-K enolate confirms the cooperative mechanism proposed by DFT calculations, where the oximate ligand has a prominent role. From these enolates the formation of new C-C bonds is straightforward.

Competitive Desulfonylative Reduction and Oxidation of α-Sulfonylketones Promoted by Photoinduced Electron Transfer with 2-Hydroxyaryl-1,3-dimethylbenzimidazolines under Air

Desulfonylation reactions of α-sulfonylketones promoted by photoinduced electron transfer with 2-hydroxyarylbenzimidazolines (BIH-ArOH) were investigated. Under aerobic conditions, photoexcited 2-hydroxynaphthylbenzimidazoline (BIH-NapOH) promotes competitive reduction (forming alkylketones) and oxidation (producing α-hydroxyketones) of sulfonylketones through pathways involving the intermediacy of α-ketoalkyl radicals. The results of an examination of the effects of solvents, radical trapping reagents, substituents of sulfonylketones, and a variety of hydroxyaryl- and aryl-benzimidazolines (BIH-ArOH and BIH-Ar) suggest that the oxidation products are produced by dissociation of α-ketoalkyl radicals from the initially formed solvent-caged radical ion pairs followed by reaction with molecular oxygen. In addition, the observations indicate that the reduction products are generated by proton or hydrogen atom transfer in solvent-caged radical ion pairs derived from benzimidazolines and sulfonylketones. The results also suggest that arylsulfinate anions arising by carbon-sulfur bond cleavage of sulfonylketone radical anions act as reductants in the oxidation pathway to convert initially formed α-hydroperoxyketones to α-hydroxyketones. Finally, density functional theory calculations were performed to explore the structures and properties of radical ions of sulfonylketones as well as BIH-NapOH.

External-oxidant-free amino-benzoyloxylation of unactivated alkenes of unsaturated ketoximes with: O -benzoylhydroxylamines

A new copper-catalyzed two-component amino-benzoyloxylation of unactivated alkenes of unsaturated ketoximes with O-benzoylhydroxylamines as the benzoyloxy sources is developed. Chemoselectivity of this method toward amino-benzoyloxylation or oxy-benzoyloxylation of alkenyl ketoximes relies on the position of the tethered olefins, and provides an external-oxidant-free alkene difunctionalization route that directly utilizes O-benzoylhydroxylamines as the benzoyloxy radical precursors and internal oxidants for the divergent synthesis of cyclic nitrones and isoxazolines.