55898-43-6

Basic information

• Product Name: DIETHYL METHYL PROPYL MALONATE
• Synonyms: DIETHYL METHYL PROPYL MALONATE;Diethyl Methylpropylpropanedioate;Diethyl 2-Methyl-2-n-propylamalonate;methylpropyl-Malonic acid. diethyl ester;2-Methyl-2-propylmalonic acid diethyl ester;Pentane-2,2-dicarboxylic acid diethyl ester;diethyl 2-methyl-2-propylpropanedioate;diethyl 2-methyl-2-propyl-propanedioate
• CAS NO: 55898-43-6
• Molecular Formula: C₁₁H₂₀O₄
• Molecular Weight: 216.27
• Product Categories: Pharmaceutical Intermediates;Miscellaneous Reagents
• Mol File: 55898-43-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 233.2°Cat760mmHg
• Flash Point: 100.3°C
• Appearance: /
• Density: 0.996g/cm³
• Vapor Pressure: 0.0565mmHg at 25°C
• Refractive Index: 1.433
• CAS DataBase Reference: DIETHYL METHYL PROPYL MALONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL METHYL PROPYL MALONATE(55898-43-6)
• EPA Substance Registry System: DIETHYL METHYL PROPYL MALONATE(55898-43-6)

Safety Data

• Hazardous Substances Data: 55898-43-6(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Uses

Diethyl 2-Methyl-2-propylmalonate is a reagent used in the preparation of anaerobic alkane biodegredation compounds.

InChI:InChI=1/C11H20O4/c1-5-8-11(4,9(12)14-6-2)10(13)15-7-3/h5-8H2,1-4H3

Upstream product

• 106-94-5 propyl bromide 
• 609-08-5 Diethyl methylmalonate 
• 105-53-3 diethyl malonate 
• 107-08-4 1-iodo-propane 
• 141-52-6 sodium ethanolate 
• 2163-48-6 diethyl propylmalonate 
• 74-88-4 methyl iodide 
• 19157-51-8 ethyl 2-ethoxycarbonyl-2-methyl-4-pentynoate 
• 53651-72-2 diethyl allylmethylmalonate 

Downstream Products

• 78-26-2 2-methyl-2-propyl-1,3-propanediol 
• 68734-78-1 2-Methyl-2-(phenylthio)-pentansaeureethylester 
• 92155-95-8 diethyl 2-(2-methylpentyl)malonate 
• 39255-32-8 manzanate 
• 105-30-6 2-methylpentan-1-ol 
• 25346-33-2 1-bromo-2-methylpentane 

Relevant articles and documents

Synthesis and mass spectra of rearrangement bio-signature metabolites of anaerobic alkane degradation via fumarate addition

Metabolite profiling in anaerobic alkane biodegradation plays an important role in revealing activation mechanisms. Apart from alkylsuccinates, which are considered to be the usual biomarkers via fumarate addition, the downstream metabolites of C-skeleton rearrangement can also be regarded as biomarkers. However, it is difficult to detect intermediate metabolites in both environmental samples and enrichment cultures, resulting in lacking direct evidence to prove the occurrence of fumarate addition pathway. In this work, a synthetic method of rearrangement metabolites was established. Four compounds, namely, propylmalonic acid, 2-(2-methylbutyl)malonic acid, 2-(2-methylpentyl)malonic acid and 2-(2-methyloctyl)malonic acid, were synthesized and determined by four derivatization approaches. Besides, their mass spectra were obtained. Four characteristic ions were observed at m/z 133 + 14n, 160 + 28n, 173 + 28n and [M - (45 + 14n)]+ (n = 0 and 2 for ethyl and n-butyl esters, respectively). For methyl esterification, mass spectral features were m/z 132, 145 and [M - 31]+, while for silylation, fragments were m/z 73, 147, 217, 248, 261 and [M - 15]+. These data provide basis on identification of potential rearrangement metabolites in anaerobic alkane biodegradation via fumarate addition.

Pd-C-induced catalytic transfer hydrogenation with triethylsilane

(Chemical Equation Presented) In situ generation of molecular hydrogen by addition of triethylsilane to palladium-charcoal catalyst results in rapid and efficient reduction of multiple bonds, azides, imines, and nitro groups, as well as benzyl group and allyl group deprotection under mild, neutral conditions.