56010-54-9Relevant academic research and scientific papers
Optical enrichment in enzyme-catalyzed resolution of 1-aryl-2,2-dimethyl-1,3-propanediols
Mukherjee, Chandrani,Mohapatra, Prabhu P.,Youssef, Dani,Jha, Amitabh
, p. 1 - 6 (2017/01/10)
Novozym 435 efficiently catalyzed the chemo-, regio-, and enantioselective transesterification of 1-aryl-2,2-dimethyl-1,3-propanediols in different organic solvents with vinyl acetate as the acetyl donor at room temperature. This enzyme-catalyzed chemical
Biheteroaromatic diphosphine oxides-catalyzed stereoselective direct aldol reactions
Rossi, Sergio,Benaglia, Maurizio,Genoni, Andrea,Benincori, Tiziana,Celentano, Giuseppe
supporting information; experimental part, p. 158 - 166 (2011/02/27)
A highly stereoselective direct aldol condensation of ketones to aromatic aldehydes was realized; the trichlorosilyl enolether generated in situ in the presence of tetrachlorosilane is activated by catalytic amounts of an enantiomerically pure biheteroaromatic phosphine oxide to react with aldehydes, coordinated as well as activated by the chiral cationic hypervalent silicon species. This Lewis acid-mediated Lewis base-catalyzed transformation allowed, starting from two carbonyl compounds, to directly synthesize β-hydroxy ketones generally with high anti stereoselectivity and up to 93% ee for the anti isomer.
Asymmetric cyclic phosphorothonamides containing substituted pyridine
Shi, De-Qing,Feras, Abudhaim,Liu, Yi
, p. 2663 - 2673 (2007/10/03)
In order to find high-acitivity and low-toxicity pesticidal lead compounds, a type of novel, asymmetric cyclic phosphorothonamides containing substituted pyridine were synthesized via the condensation reactions of 2-chloro-4- substitutedphenyl-5,5-dimethy
Lithium acetate-catalyzed crossed aldol reaction between aldehydes and trimethylsilyl enolates generated from other aldehydes
Kawano, Yoshikazu,Fujisawa, Hidehiko,Mukaiyama, Teruaki
, p. 614 - 615 (2007/10/03)
Crossed aldol reaction between aromatic aldehydes having an electron-withdrawing group and trimethylsilyl enolates generated from several aldehydes proceeded smoothly in dry or water-containing DMF in the presence of a catalytic amount of a Lewis base such as lithium acetate or lithium benzoate. Successive reduction of the produced aldehydes with sodium borohydride (NaBH4) afforded the corresponding 1,3-diols in good to high yields in one-pot. Copyright
Synthesis and biological activity of cis 2-(6-chloropyridine-3-yl) methylamino-4-substitutedphenyl-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxides
De, Qing Shi,Liu, Yi,Feras,Xiao, Song Tan,Jian, Xin Chen
, p. 1937 - 1946 (2007/10/03)
A series of novel, asymmetric-cyclic phosphoramides containing substituted pyridine were synthesized via the condensation reactions of trans 2-chloro-4-substitutedphenyl-5, 5-dimethyl-1,3,2-dioxaphosphinane 2-oxide with 2-chloro-5-aminomethylpyridine or 3
