620597-33-3Relevant academic research and scientific papers
Catalytic anions embedded into avidin: Importance of their chirality and the chiral environment on the stereocontrol of the aldol reaction
Gauchot, Vincent,Schmitzer, Andreea R.
, p. 2694 - 2701 (2014/04/17)
Several catalytic anions bearing a pseudo-dipeptide scaffold, in combination with a biotinylated imidazolium cation, were prepared. The assembly of these salts with avidin resulted in the formation of stable biohybrid catalysts, active in ionic liquid/aqueous media for the aldol reaction. By using natural and non-natural amino alcohols as "side chains" for the proline derivative anion, we studied the cooperativity between the anion and its position in avidin. Taking advantage of the large freedom of movement of the anion inside avidin, we also investigated the substrate scope of this type of biohybrid catalyst.
Germanium(II)-mediated reductive cross-aldol reaction of aldehydes: Synthesis of aldols with diastereocontrolled quaternary carbon centers
Tanaka, Shin-Ya,Yasuda, Makoto,Baba, Akio
, p. 1720 - 1724 (2008/02/11)
anti-Selective synthesis of aldols with quaternary carbon centers was achieved by germanium(II)-mediated reductive cross-aldol reaction of tertiary α-bromo aldehydes with both aromatic and aliphatic aldehydes. One-pot direct reduction and reductive aminat
Rapid Fluorescent Screening for Bifunctional Amine-Acid Catalysts: Efficient Syntheses of Quaternary Carbon-Containing Aldols under Organocatalysis
Mase, Nobuyuki,Tanaka, Fujie,Barbas III, Carlos F.
, p. 4369 - 4372 (2007/10/03)
(Equation presented) Direct catalytic aldol reactions of α.α-dialkylaldehyde donors and arylaldehyde acceptors have been performed using pyrrolidine-acetic acid bifunctional catalysts. This general and practical amine-acid combination was identified by sc
