56024-62-5Relevant articles and documents
Gold-catalyzed diastereoselective synthesis of α-fluoroenones from propargyl acetates
Hopkinson, Matthew N.,Giuffredi, Guy T.,Gee, Antony D.,Gouverneur, Véronique
supporting information; experimental part, p. 2737 - 2742 (2010/12/25)
A diastereoselective preparation of -fluoroenones from propargyl acetates has been developed proceeding via a gold-catalyzed rearrangement-fluorination cascade. Control reactions are consistent with a mechanism involving a gold-mediated 3,3-sigmatropic shift followed by a direct, nongold-catalyzed electrophilic fluorination of the allenyl acetate intermediate.
