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56052-26-7

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56052-26-7 Usage

General Description

(1-Bromonaphthalen-4-yl)methanol is a chemical compound with the molecular formula C11H9BrO. It is a derivative of naphthalene containing a bromine atom and a hydroxyl group. The compound is primarily used as a building block for the synthesis of various pharmaceuticals, agrochemicals, and dyes. It is also used in research and development as a reagent in organic synthesis. (1-Bromonaphthalen-4-yl)methanol is known to have moderate toxicity and should be handled with care in a laboratory setting. Its properties and applications make it important in the field of organic chemistry and drug development.

Check Digit Verification of cas no

The CAS Registry Mumber 56052-26-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,0,5 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 56052-26:
(7*5)+(6*6)+(5*0)+(4*5)+(3*2)+(2*2)+(1*6)=107
107 % 10 = 7
So 56052-26-7 is a valid CAS Registry Number.

56052-26-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-bromonaphthalen-1-yl)methanol

1.2 Other means of identification

Product number -
Other names 1-Naphthalenemethanol,4-bromo

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:56052-26-7 SDS

56052-26-7Relevant articles and documents

Pd-catalyzed allylative dearomatisation using Grignard reagents

Boldrini, Cosimo,Harutyunyan, Syuzanna R.

supporting information, p. 11807 - 11810 (2021/11/30)

Pd-catalyzed allylative dearomatisation of naphthyl halides is shown to be feasible by employing Grignard reagents. The high reactivity of the nucleophile allows for fast reactions and low catalyst loading, while a plethora of successfully substituted compounds illustrate the broad scope. Five membered heteroaromatic compounds are also demonstrated to be reactive under similar conditions.

ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS

-

Paragraph 1747; 1748, (2015/05/13)

The present invention relates to novel and inventive isoxazoline of formula (I) and salts thereof: wherein variables D1, D2, D3, D4, D5, R1, B1, B2, B3, R2, R3, R4, R5, R6, Y, Z, L, a and b are described herein are as defined in the description. The invention also relates to parasiticidal and pesticidal compositions comprising the isoxazoline compounds of formula (I), processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.

CYP17 inhibitors. Annulations of additional rings in methylene imidazole substituted biphenyls: Synthesis, biological evaluation and molecular modelling

Pinto-Bazurco Mendieta, Mariano A. E.,Negri, Matthias,Hu, Qingzhong,Hille, Ulrike E.,Jagusch, Carsten,Jahn-Hoffmann, Kerstin,Mueller-Vieira, Ursula,Schmidt, Dirk,Lauterbach, Thomas,Hartmann, Rolf W.

experimental part, p. 547 - 609 (2009/04/04)

Twenty-one novel compounds originating from two classes of annulated biphenyls were synthesized as mimetics of the steroidal A- and C-rings and examined for their potency as inhibitors of human CYP17. Selected compounds were tested for inhibition of the hepatic CYP enzyme 3A4. Potent CYP17 inhibitors were found for each class, compound 9 (17 and 71% at 0.2 and 2 μM, respectively) and 21 (591 nM). Compound 21 showed only weak inhibition of CYP3A4 (32 and 64% at 2 and 10 μM, respectively). Both compounds, however, exhibited moderate to strong inhibition of the glucocorticoid-forming enzyme CYP11B1. The most interesting compounds were docked into our protein model. They bound into one of the modes which we have previously published. New interaction regions were identified.

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