56066-91-2

Usage

Uses

Used in Pharmaceutical Industry:
p-Chloro-methylphenyl acetic acid is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of medications with anti-inflammatory and analgesic effects. Its role in inhibiting cyclooxygenase makes it a valuable component in the creation of drugs aimed at treating conditions like rheumatoid arthritis and other inflammatory disorders.
Used in Agrochemical Industry:
Although the provided materials do not explicitly mention its use in agrochemicals, p-Chloro-methylphenyl acetic acid's common use as an intermediate in the synthesis of agrochemicals suggests that it may be utilized in the development of products for agricultural applications, potentially including pesticides or herbicides, due to its chemical properties.
Used in Inflammatory Condition Treatment:
p-Chloro-methylphenyl acetic acid is used as a potential treatment for inflammatory conditions such as rheumatoid arthritis, leveraging its anti-inflammatory and analgesic properties to alleviate symptoms and improve patient outcomes.
Used in Enzyme Inhibition Studies:
As a potent inhibitor of cyclooxygenase, p-Chloro-methylphenyl acetic acid is used in research and development for studying enzyme inhibition mechanisms, which can be crucial for understanding and treating a variety of inflammatory and pain-related conditions.

Upstream product

• 103-82-2 phenylacetic acid 
• 50-00-0 formaldehyd 
• 13737-36-5 4-bromophenylacetic acid 
• 118618-41-0 [4-(hydroxymethyl)phenyl]acetic acid ethyl ester 
• 107-30-2 chloromethyl methyl ether 
• 622-47-9 4-tolylacetic acid 
• 43153-12-4 ethyl 2-(4-formylphenyl)acetate 
• 1528-41-2 ethyl 4-cyanophenylacetate 

Downstream Products

• 1200-05-1 2-(4-(aminomethyl)phenyl)acetic acid 
• 177712-50-4 [4-(diethoxyphosphinyl)methyl]-phenylacetic acid 
• 56097-33-7 4-chloromethylphenylacetyl chloride 
• 103-82-2 phenylacetic acid 
• 148113-97-7 2-(4-Chloromethyl-phenyl)-N-{6-[2-(4-chloromethyl-phenyl)-acetylamino]-pyridin-2-yl}-acetamide 
• 142327-25-1 (E)-2-(4-styrylphenyl)acetatic acid 

Relevant academic research and scientific papers

Ketonization of the unusually acidic elongated enol generated by flash photolytic decarboxylation of p-formylphenylacetic acid in aqueous solution

Rates of photolysis of p-formylphenylacetic acid were measured flash photoytically in perchloric acid and sodium, hydroxide solutions, and also in acetic acid, biphosphate ion, and tris-(hydroxym.ethyl)methaneam.monium ion buffers, using H2O and D2O as solvents. The results provide rate profiles and solvent isotope effects, which indicate that photolysis occurs through an elongated enol intermediate. This enol is unusually strongly acidic, by some two to three pQa units, when compared with simple non-elongated enols.

Triazole derivatives

The present invention relates to triazole and imidazole derivatives of formula I and to their pharmaceutically acceptable acid addition salts. These compounds are NMDA receptor subtype blockers and are useful for the treatment of diseases related to the NMDA receptor.

trans-4-Stilbenecarboxylatoalkylpentaamminecobalt(III) perchlorates: Synthesis and intramolecular energy transfer

Three homologs of tran-4-stilbenecarboxylic acid, viz., trans-4-stilbeneacetic acid (18), β-(trans-4-stilbene)propionic acid (19), and γ-trans-4-stilbene)butyric acid (20) were synthesized and, together with the parent trans-4-stilbenecarboxylic acid, use

A Novel Receptor for Dicarboxylic Acid Derivatives

A novel receptor 4 has been prepared, which binds the monopotassium salts of various dicarboxylic acids in chloroform solution, using a combination of hydrogen bonding interactions and an electrostatic association between a carboxylate anion and a crown e

Cephalosporin antibiotics

Novel cephalosporin antibiotic derivatives.

Cephalosporin antibiotics

Novel cephalosporin antibiotic derivatives.

Cephalosporin antibiotics

Novel cephalosporin antibiotic derivatives.

Isothiourea substituted cephalosporin derivatives

Novel cephalosporin and penicillin antibiotic derivatives.