561280-07-7

Basic information

• Product Name: 5,7-Methanoisoquinoline, 3-(2-fluorophenyl)-5,6,7,8-tetrahydro-6,6,8-trimethyl-, (5S,7S,8R)-
• CAS NO: 561280-07-7
• Molecular Formula: C19H20FN
• Molecular Weight: 281.373
• Mol File: 561280-07-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5,7-Methanoisoquinoline, 3-(2-fluorophenyl)-5,6,7,8-tetrahydro-6,6,8-trimethyl-, (5S,7S,8R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-Methanoisoquinoline, 3-(2-fluorophenyl)-5,6,7,8-tetrahydro-6,6,8-trimethyl-, (5S,7S,8R)-(561280-07-7)
• EPA Substance Registry System: 5,7-Methanoisoquinoline, 3-(2-fluorophenyl)-5,6,7,8-tetrahydro-6,6,8-trimethyl-, (5S,7S,8R)-(561280-07-7)

Safety Data

• Hazardous Substances Data: 561280-07-7(Hazardous Substances Data)

Upstream product

• 19890-00-7 (1S)-pinocarvone 
• 445-27-2 2'-Fluoroacetophenone 
• 7785-26-4 (-)-α-pinene 
• 409319-21-7 (1S,9S)-(+)-5-(2-fluorophenyl)-10,10-dimethyl-6-azatricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-triene 
• 74-88-4 methyl iodide 

Downstream Products

• 561280-12-4 C₁₉H₂₀FNO 

Relevant articles and documents

Mechanistic dichotomy in the asymmetric allylation of aldehydes with allyltrichlorosilanes catalyzed by chiral pyridine N-oxides

Detailed kinetic and computational investigation of the enantio- and diastereoselective allylation of aldehydes 1 with allyltrichlorosilanes 5, employing the pyridine N-oxides METHOX (9) and QUINOX (10) as chiral organocatalysts, indicate that the reaction can proceed through a dissociative (cationic) or associative (neutral) mechanism: METHOX apparently favors a pentacoordinate cationic transition state, while the less sterically demanding QUINOX is likely to operate via a hexacoordinate neutral complex. In both pathways, only one molecule of the catalyst is involved in the rate- and selectivity-determining step, which is supported by both experimental and computational data. Copyright