561297-90-3

Upstream product

• 123-75-1 pyrrolidine 
• 42206-47-3 2-methyl-2-(4-nitro-phenyl)-propionic acid 
• 83397-45-9 ethyl 2-methyl-2-(4-nitrophenyl)propanoate 
• 40919-12-8 2-methyl-2-(4-nitro-phenyl)-propionyl chloride 

Downstream Products

• 1135496-66-0 1-[2-methyl-2-(4-nitro-phenyl)-propyl]-pyrrolidine 

Relevant academic research and scientific papers

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

Substituted alkylamine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.