56139-76-5

Basic information

• Product Name: DIMETHYL-(1-METHYL-1H-PYRROL-2-YLMETHYL)-AMINE
• Synonyms: DIMETHYL-(1-METHYL-1H-PYRROL-2-YLMETHYL)-AMINE;N,N,1-trimethyl-1H-pyrrole-2-methylamine;1-METHYL-2-(DIMETHYLAMINOMETHYL)PYRROLE;1H-Pyrrole-2-methanamine, N,N,1-trimethyl-;n,n,1-trimethyl-1h-pyrrole-2-methanamin;N,N,1-Trimethyl-1H-pyrrole-2-methanamine;2-Dimethylaminomethyl-1-methylpyrrole;Einecs 260-011-3
• CAS NO: 56139-76-5
• Molecular Formula: C₈H₁₄N₂
• Molecular Weight: 138.21016
• EINECS: 260-011-3
• Mol File: 56139-76-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 180.5°C at 760 mmHg
• Flash Point: 63°C
• Appearance: /
• Density: 0.91g/cm³
• Vapor Pressure: 0.891mmHg at 25°C
• Refractive Index: 1.495
• CAS DataBase Reference: DIMETHYL-(1-METHYL-1H-PYRROL-2-YLMETHYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL-(1-METHYL-1H-PYRROL-2-YLMETHYL)-AMINE(56139-76-5)
• EPA Substance Registry System: DIMETHYL-(1-METHYL-1H-PYRROL-2-YLMETHYL)-AMINE(56139-76-5)

Safety Data

• Hazardous Substances Data: 56139-76-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H14N2/c1-9(2)7-8-5-4-6-10(8)3/h4-6H,7H2,1-3H3

Upstream product

• 96-54-8 N-Methylpyrrole 
• 50-00-0 formaldehyd 
• 506-59-2 N,N-dimethylammonium chloride 
• 124-40-3 dimethyl amine 
• 62992-33-0 ethoxy-N,N-dimethylaminomethane 
• 51-80-9 bis-(dimethylamino)methane 

Downstream Products

• 24437-41-0 1-methyl-2-pyrroleacetonitrile 
• 676486-43-4 1-methyl-4,6-dihydrocyclopenta[b]pyrrol-5-one 
• 21898-59-9 1-methylpyrrole-2-acetic acid 

Relevant articles and documents

AMINO ALCOHOL COMPOUND

A pharmaceutical composition is provided that has a low toxicity, demonstrates superior physicochemical properties and pharmacokinetics, and has superior peripheral blood lymphocyte count lowering activity. The pharmaceutical composition contains a compound having general formula (I): (wherein R 1 represents a methyl group or an ethyl group, R 2 represents a methyl group or an ethyl group, and R 3 represents a phenyl group substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a cycloalkyl group, a lower alkoxy group, a halogeno lower alkyl group, a lower aliphatic acyl group and a cyano group), a pharmacologically acceptable salt thereof or a pharmacologically acceptable ester thereof.

Rhodium(II) catalyzed intramolecular insertion of carbenoids derived from 2-pyrrolyl and 3-indolyl α-diazo-β-ketoesters and α-diazoketones

α-Diazo-β-ketoesters and α-diazoketones derived from 2-pyrrolylacetic, 2-pyrrolylpropionic, 3-indolylacetic and 3-indolylpropionic acids afforded carbenoid derived cyclization products on treatment with catalytic rhodium(II) acetate.

The generation of iminium ions using chlorosilanes and their reactions with electron rich aromatic heterocycles

Dichlorodimethylsilane and trichloromethylsilane have been used to generate iminium ions from aminals and aminol ethers derived from secondary alkylamines, including glycine derivatives, in aprotic media which were shown to undergo reactions with electron rich aromatic heterocycles, including furan, to give mono-aminoalkylation products in good yields. Whereas chlorotrimethylsilane has been shown to generate iminium ions from aminol ethers, no evidence was adduced for the involvement of iminium ions using aminals. 2,5-Disubstitution of N-methylpyrrole was the major result in reactions of N-methylpyrrole with aminals in the presence of chlorotrimethylsilane where no build up of hydrogen chloride occurs and where chlorotrimethylsilane can function catalytically. Experimental results, including the use of bis(trimethylsilyl)acetamide as a proton scavenger, and some relative rate data, are presented that allow possible mechanisms to be evaluated.