56207-40-0Relevant academic research and scientific papers
Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B- adrenoceptor antagonist
Fumagalli, Laura,Pallavicini, Marco,Budriesi, Roberta,Gobbi, Marco,Straniero, Valentina,Zagami, Michael,Chiodini, Giuseppe,Bolchi, Cristiano,Chiarini, Alberto,Micucci, Matteo,Valoti, Ermanno
, p. 184 - 191 (2013/02/23)
Unichiral 8-substituted analogues of 2-[(2-(2,6-dimethoxyphenoxy)ethyl) aminomethyl]-1,4-benzodioxane (WB4101) were synthesized and tested for binding affinity at cloned human α1a-, α1b-and α1d-adrenoreceptor (α1a/su
QSAR study for?a?novel series of?ortho disubstituted phenoxy analogues of?α1-adrenoceptor antagonist WB4101
Pallavicini,Fumagalli,Gobbi,Bolchi,Colleoni,Moroni,Pedretti,Rusconi,Vistoli,Valoti
, p. 1025 - 1040 (2007/10/03)
On the basis of the affinities at the α1a-, α1b- and α1d-adrenoceptors and the 5-HT1A receptor of a previous series of sixteen 2-[(2-phenoxyethyl)aminomethyl]-1,4-benzodioxanes ortho monosubstituted at the pheno
