56279-49-3Relevant academic research and scientific papers
The acylphosphonate function as an activating and masking moiety for the α-chlorination of fatty acids
Stevens, Christian,De Buyck, Laurent,De Kimpe, Norbert
, p. 8739 - 8742 (2007/10/03)
α-Chloroacylphosphonates were prepared in situ by chlorination of acylphosphonates using sulfuryl chloride and were subsequently cleaved to the corresponding α-chlorinated fatty acids with hydrogen peroxide - sodium bicarbonate.
A convenient synthesis of α-fluoro carboxylic acids
Oliver,Waters,Lusby
, p. 273 - 275 (2007/10/02)
Conditions have been developed whereby treatment of 1,1,1-trichloro-2- carbinols with tetrabutylammonium fluoride and cesium fluoride provides 2- fluoro carboxylic acids. The methodology was used to prepare fluoro derivatives of two fatty acids and of the pheromone of the European corn borer.
