629-22-1

Basic information

• Product Name: DL-A-HYDROXYSTEARIC ACID
• Synonyms: DL-A-HYDROXYSTEARIC ACID;dl-α-hydroxystearic acid
• CAS NO: 629-22-1
• Molecular Formula: C₁₈H₃₆O₃
• Molecular Weight: 300.47664
• Mol File: 629-22-1.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 432.6°C at 760 mmHg
• Flash Point: 229.6°C
• Appearance: /
• Density: 0.944g/cm³
• Vapor Pressure: 2.67E-09mmHg at 25°C
• Refractive Index: 1.468
• Storage Temp.: 2-8°C
• CAS DataBase Reference: DL-A-HYDROXYSTEARIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DL-A-HYDROXYSTEARIC ACID(629-22-1)
• EPA Substance Registry System: DL-A-HYDROXYSTEARIC ACID(629-22-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 629-22-1(Hazardous Substances Data)

Usage

Description

2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U. armoricana. It reduces growth of Ehrlich ascites tumor (EAT) cells in vitro when used at a concentration of 100 μM. Levels of 2-hydroxy stearic acid are elevated in human joint synovial fluid after ankle fracture and in patients with Buruli ulcer disease. [Matreya, LLC. Catalog No. 1707]

Definition

ChEBI: A long-chain fatty acid that is stearic (octadecanoic) acid substituted at position 2 by a hydroxy group.

InChI:InChI=1/C18H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(19)18(20)21/h17,19H,2-16H2,1H3,(H,20,21)/t17-/m1/s1

Upstream product

• 56279-49-3 2-chloro-octadecanoic acid 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 
• 5829-46-9 9-chloro-octadecanoic acid 
• 60-29-7 diethyl ether 
• 64-17-5 ethanol 
• 142-94-9 2-bromostearic acid 
• 3196-18-7 Methyl 2-bromostearate 
• 57-11-4 stearic acid 
• 2420-35-1 2-hydroxyoctadecanoic acid methyl ester 
• 41753-99-5 2-chloro-octadecanoic acid methyl ester 

Downstream Products

• 629-90-3 n-heptadecanal 
• 7378-88-3 12-octadecenoic acid 
• 506-12-7 heptadecanoic acid 
• 56279-49-3 2-chloro-octadecanoic acid 
• 64-18-6 formic acid 
• 7732-18-5 water 
• 41753-99-5 2-chloro-octadecanoic acid methyl ester 
• 67491-95-6 2-(2-Hydroxyethylamino)octadecanoic acid 
• 100896-30-8 (2R)-2-hydroxyoctadecanoic acid methyl ester 
• 405167-20-6 2-acetoxy-octadecanoic acid pentafluorophenyl ester 
• 2420-35-1 2-hydroxyoctadecanoic acid methyl ester 

Relevant articles and documents

Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents

A series of α- and β-carboxylated phospholipid prodrugs of dideoxy nucleosides have been synthesized and evaluated against HIV. An increase in biological effect with a factor of 500 has only been observed for the adenine nucleoside, which suggests that this prodrug approach is base specific.

Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and at least one oil with a molar mass of 650 to 10 000 g/mol

Disclosed herein is a composition, for example, a cosmetic care and/or makeup composition for a keratin material, comprising, in a cosmetically acceptable medium, i) at least one polyester resulting from esterification of at least one triglyceride of at least one hydroxylated carboxylic acid with at least one aliphatic monocarboxylic acid and at least one aliphatic dicarboxylic acid, ii) at least one oil of a molar mass ranging from 650 to 10 000 g/mol, and iii) at least one colorant. The composition may possess cosmetic properties and can, for example, endow the makeup or care product with properties of gloss, smoothness of application and comfort. Further disclosed herein is the use of the at least one polyester and the at least one oil with a molar mass ranging from 650 to 10 000 g/mol in a physiologically acceptable composition as an agent for endowing the composition with properties of slip, gloss, comfort, definition, non-migration, enhanced color intensity and/or enhanced color retention after challenge.

POWDERED COSMETIC COMPOSITIONS CONTAINING SILICONE ELASTOMERS

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