56308-05-5

Upstream product

• 107-31-3 Methyl formate 
• 56308-01-1 2'-hydroxy-4'-methoxy-2-(phenylthio)acetophenone 
• 73220-33-4 3-(dimethylamino)-1-(4-ethoxy-2-hydroxyphenyl)prop-2-en-1-one 
• 80-17-1 benzenesufonyl hydrazide 
• 5751-52-0 7-methoxy-4H-chromen-4-one 
• 882-33-7 diphenyldisulfane 
• 108-98-5 thiophenol 
• 56307-99-4 2',4'-dihydroxy-2-phenylthioacetophenone 

Downstream Products

• 56308-01-1 2'-hydroxy-4'-methoxy-2-(phenylthio)acetophenone 

Relevant academic research and scientific papers

Ammonium iodide-mediated regioselective chalcogenation of chromones with diaryl disulfides and diselenides

A metal-free method for the synthesis of 3-chalcogenyl-chromones/quinolones from chromones/quinolones and diorganyl dichalcogenides using ammonium iodide under air was developed. This approach allowed the preparation of a wide range of 3-selenyl- and 3-sulfenyl-chromones/quinolones in good to excellent yields.

Transition-metal-free synthesis of 3-sulfenylated chromones via KIO3-catalyzed radical C(sp2)–H sulfenylation

The reactions between o-hydroxylphenyl-functionalized enaminones and sulfonyl hydrazines providing 3-sulfenylated chromones via domino chromone ring construction and C(sp2)–H bond sulfenylation have been achieved under transition-metal-free conditions by using KIO3 as the only catalyst.

SYNTHESIS OF 3-PHENYLTHIOCHROMONES FROM 2'-HYDROXY-2-PHENYLTHIOACETOPHENONES

2'-Hydroxy-2-phenylthioacetophenone derivatives (4a, b) can be readily prepared either from 2'-hydroxy-2-halogenoacetophenones (1a-c) and thiophenol, or from phenylthioacetonitrile and polyphenols (route 4b, c).The partial methylation reaction of 4b is co