56309-54-7

Upstream product

• 54948-58-2 2,4-dinitrobenzoyl azide 
• 108-88-3 toluene 
• 56-23-5 tetrachloromethane 
• 610-30-0 2,4-dinitrobenzoic acid 
• 20195-22-6 2,4-dinitrobenzoyl chloride 

Downstream Products

• 118619-47-9 3-(2,4-dinitrophenyl)-1-ethyl-1-phenylurea 
• 77298-07-8 2-(2,4-Dinitrophenyl)-5,5,9,9-tetramethyl-3-thioxo-2-azaspiro<3.5>nonan-1-on 
• 118619-48-0 1-(2,4-dinitrophenyl)-3-(2-nitrophenyl)urea 
• 118619-49-1 1-(2,4-dinitrophenyl)-3-(4-nitrophenyl)urea 

Relevant academic research and scientific papers

N- and O-Alkylations of Nitro-Substituted 1,3-Diphenylureas: Preparations of Propellant Stabilizer Derivatives

A procedure has been developed for the N-ethylation and methylation of 1,3-diphenylureas, ArNRCONHAr' (R=H, Me or Et), through treatment with sodium hydride and iodoalkane in dimethylformamide.The reaction was general, provided that the aniline to be alkylated was substituted with no more than one nitro group.ArRNCONR'Ar' derivatives prepared were: R = R'= Et (and Me); Ar = phenyl, Ar' = 2-nitrophenyl and 4-nitrophenyl; Ar = 2-nitrophenyl, Ar' = 2-nitrophenyl and 4-nitrophenyl; Ar = Ar' = 4-nitrophenyl.Two mixed derivatives were also prepared: R = Et, R' = Me, Ar = phenyl, Ar' = 2-nitrophenyl and 4-nitrophenyl.O-Alkylated isourea products were obtained in the reactions of 1-(2,4-dinitrophenyl)-3-(2-nitrophenyl)urea and 1-(2,4-dinitrophenyl)-3-(4-nitrophenyl)urea.The use of potassium carbonate as the base led to apparently exclusive O-alkylation of 1,3-bis(2-nitrophenyl)urea although the reaction was not general. 1-(2,4-Dinitrophenyl)-1,3-diethyl-3-phenylurea was prepared by using silver oxide and obtained as a mixture with the isourea.Many of the compounds prepared are important nitro derivatives of the propellant stabilizers, ethyl and methyl centralite.

Synthesis of isocyanates from nitroalkanes

A process for the preparation of aromatic isocyanates from nitroalkanes. A nitromethyl aromatic compound of the general formula: STR1 wherein R and R1 represent hydrogen, halogen, a C1 -C5 alkyl radical, a C1 -C4 alkoxy radical, nitro, isocyanato, an alkoxycarbonylamino, or nitromethyl radical, with R and R1 being the same or different, is heated in the presence of an effective amount of a Lewis acid or Bronsted acid substance to effect a dehydrogenation-isomerization reaction to yield an aromatic isocyanate of the general formula: STR2 The product of the reaction may be recovered as the aromatic isocyanate or the alcohol adduct, a carbamate.