56309-59-2

Usage

Uses

Used in Chemical and Manufacturing Industries:
2-METHYL-4-NITROPHENYL ISOCYANATE is used as a key chemical intermediate for the synthesis of various compounds due to its high reactivity with a range of other chemicals. This makes it valuable in the development of new materials and products within these industries.
Used in the Production of Polyurethane Foams:
2-METHYL-4-NITROPHENYL ISOCYANATE is used as a reactant in the production of polyurethane foams for its ability to form stable and versatile polymers. These foams are utilized in a variety of applications, including insulation, cushioning, and as a component in various consumer and industrial products.
Used in Research and Development:
2-METHYL-4-NITROPHENYL ISOCYANATE is used as a research compound for studying its chemical properties and potential applications in new technologies and materials. Its reactivity allows scientists to explore its interactions with other compounds, potentially leading to innovative uses in various fields.

InChI:InChI=1/C8H6N2O3/c1-6-4-7(10(12)13)2-3-8(6)9-5-11/h2-4H,1H3

Upstream product

• 75-44-5 phosgene 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 503-38-8 trichloromethyl chloroformate 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 56799-61-2 (2-methyl-4-nitro-phenyl)-carbamic acid methyl ester 
• 117460-69-2 N-(2-methyl-4-nitrophenyl)-3,4-dihydro-2-methyl-1,3-oxo-2H-<1>benzothieno<3,2-e>-1,2-thiazine-4-carboxamide 1,1-dioxide 
• 1119860-30-8 N-(2-methyl-4-nitrophenyl)-N'-(1H-indazol-3-yl)urea 
• 199460-26-9 N-(3-fluorophenyl)-N'-(2-methyl-4-nitrophenyl)urea 
• 1356835-86-3 C₁₂H₁₈N₂O₂ 
• 1248134-80-6 C₁₁H₁₆N₂O₂ 
• 766519-08-8 (4-amino-2-methylphenyl)-carbamic acid propyl ester 
• 1310549-86-0 C₁₈H₁₆N₄O₃ 
• 1310550-11-8 C₁₈H₁₈N₄O 
• 104479-00-7 N-(4-amino-2-methylphenyl)carbamic acid methyl ester 
• 939971-04-7 1,3,5-tris-(4-nitro-2-methyl-phenyl)-[1,3,5]triazinane-2,4,6-trione 
• 70274-51-0 3-hydroxy-2-methyl-4-(2-methyl-4-nitrophenylcarbamoyl)-2H-thieno[3,4-e]-1,2-thiazine 1,1-dioxide 
• 70274-42-9 3-hydroxy-2-methyl-4-(2-methyl-4-nitrophenylcarbamoyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide 
• 869786-70-9 (2-methyl-4-nitro-phenyl)-carbamic acid 4-chloro-butyl ester 

Relevant academic research and scientific papers

Design, Synthesis and Discovery of N,N’-Carbazoyl-aryl-urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication

The recent outbreaks of Zika virus (ZIKV) infection worldwide make the discovery of novel antivirals against flaviviruses a research priority. This work describes the identification of novel inhibitors of ZIKV through a structure-based virtual screening approach using the ZIKV NS5-MTase. A novel series of molecules with a carbazoyl-aryl-urea structure has been discovered and a library of analogues has been synthesized. The new compounds inhibit ZIKV MTase with IC50 between 23–48 μM. In addition, carbazoyl-aryl-ureas also proved to inhibit ZIKV replication activity at micromolar concentration.

Method to produce hyperpolarised carboxylates

The invention relates to a dynamic nuclear polarisation method for producing hyperpolarised carboxylates of organic amines and amino compounds and compositions for use in that method. The DNP agent preferably is a stable oxygen-based, sulphur-based or car

METHOD TO PRODUCE HYPERPOLARISED CARBOXYLATES AND SULPHONATES

The invention relates to a dynamic nuclear polarisation method for producing hyperpolarised carboxylates or sulphonates or mixtures thereof wherein the carboxylate or sulphonate used in the method of the invention comprises certain inorganic cations. The

Imidazolidine Derivatives, Uses Therefor, Preparation Thereof and Compositions Comprising Such

Compounds of formula (I): wherein X is O or S, R1 is acyl, aldehyde, cycloalkyl, an optionally substituted alkyl, alkenyl or alkynyl, R2 is H. alkyl, hydroxyalkyl, haloalkyl, alkenyl, or alkynyl; substituted alkyl; alkylcarbonyl; R3 and R4 are H, halogen, alkyl, alkenyl, alkynyl, alkoxyl, alkylthio, hydroxyalkyl, haloalkyl, haloalkenyl, or haloalkynyl; or R3 and R4 form an, optionally aromatic or heterocyclic, optionally substituted ring, R5 is H, halogen, trifluoromethyl, —CN, or —NO2; not all of R3, R4, and R5 being H, R6 and R9 are H, halogen, OH; alkyl. hydroxyalkyl, alkoxyl, thioalkyl, haloalkyl, alkenyl, or alkynyl; R7 and R8 are H, halogen, OH, SH; alkoxyl or alkylthio optionally substituted by OH and/or halogen; one of R7 and R8 not being H or halogen; or one of R7 and R8 is a pharmaceutically acceptable ester or thioester grouping, or R6 is C1-3-alkyl or, together with either R1 or R2, represents C1-3 alkylene or alkenylene linking group, optionally substituted by methyl, trifluoromethyl, OH, or halogen, and pharmaceutically acceptable salts and esters thereof, are useful as selective androgen modulators.

Method of Dynamic Nuclear Polarisation DNP

The invention relates to a method of dynamic nuclear polarisation (DNP) using a combination of a trityl radical and a paramagnetic metal ion as the polarising agent leading to enhanced levels of polarisation in the sample to be polarised and to compositio

Method to Produce Hyperpolarised Carboxylates

The invention relates to a dynamic nuclear polarisation method for producing hyperpolarised carboxylates of organic amines and amino compounds and compositions for use in that method. The DNP agent preferably is a stable oxygen-based, sulphur-based or car

MULTIMERIC MAGENTIC RESONANCE CONTRAST AGENTS

The present invention relates to novel compounds of formula (I) and (II), compositions comprising compounds of formula (II) and their use as contrast agents in magnetic resonance (MR) imaging (MRI) and MR spectroscopy (MRS).

NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS

The invention relates to novel substituted thiophene-2-carboxamides of general formula (I), in which A, and R1 to R8c are defined as cited in claim 1. The invention also relates to the tautomers, enantiomers, diastereomers, mixtures and salts, in particular the physiologically compatible salts of said compounds containing inorganic or organic acids or bases, which exhibit valuable properties.