5632-81-5

Basic information

• Product Name: 2-CHLORO-3,5-DIAMINOPYRIDINE
• Synonyms: 2-CHLORO-3,5-DIAMINOPYRIDINE;2-Chloropyridine-3,5-diamine;2-chloro-3,5-Pyridinediamine
• CAS NO: 5632-81-5
• Molecular Formula: C₅H₆ClN₃
• Molecular Weight: 143.57424
• Product Categories: pharmacetical;Pyridine
• Mol File: 5632-81-5.mol

Chemical Properties

• Melting Point: 101-103 °C
• Boiling Point: 403.6 °C at 760 mmHg
• Flash Point: 197.9 °C
• Appearance: /
• Density: 1.447g/cm³
• Vapor Pressure: 1E-06mmHg at 25°C
• Refractive Index: 1.685
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.04±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-3,5-DIAMINOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3,5-DIAMINOPYRIDINE(5632-81-5)
• EPA Substance Registry System: 2-CHLORO-3,5-DIAMINOPYRIDINE(5632-81-5)

Safety Data

• Hazardous Substances Data: 5632-81-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-3,5-diaminopyridine is used as a key intermediate in the synthesis of pharmaceuticals for its potential role in the development of new therapeutic agents. It contributes to the creation of antiviral and anticancer drugs, highlighting its importance in advancing medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 2-chloro-3,5-diaminopyridine is utilized as a building block in the formulation of various agrochemicals, playing a crucial part in enhancing crop protection and yield.
Used in Dye and Pigment Industry:
2-CHLORO-3,5-DIAMINOPYRIDINE is used as a precursor in the production of dyes and pigments, where its chemical properties allow for the creation of a wide range of colorants for different applications.
Used in Polymer and Specialty Chemicals Production:
2-Chloro-3,5-diaminopyridine serves as a vital component in the synthesis of polymers and specialty chemicals, contributing to the development of innovative materials with unique properties.
Used in Corrosion Inhibition:
It has been studied for its potential use as a corrosion inhibitor, indicating its application in protecting materials from degradation in various industrial settings.
Used in Electronic Materials:
2-Chloro-3,5-diaminopyridine is also considered as a component in materials for electronic applications, suggesting its role in advancing technology through its incorporation into electronic devices and components.

InChI:InChI=1/C5H6ClN3/c6-5-4(8)1-3(7)2-9-5/h1-2H,7-8H2

Upstream product

• 2578-45-2 2-chloro-3,5-dinitropyridine 
• 7439-89-6 iron 
• 5418-51-9 5-nitro-2-hydroxypyridine 
• 2980-33-8 2-hydroxy-3,5-dinitropyridine 

Downstream Products

• 1178587-10-4 C₁₇H₂₆N₄O₄ 
• 1311968-38-3 C₂₇H₄₂N₄O₈ 
• 1178587-21-7 C₃₃H₅₆N₄O₈Si 
• 1178587-28-4 C₃₃H₅₆N₄O₈Si 
• 1178587-09-1 C₁₆H₂₄N₄O₄ 
• 1178587-15-9 C₁₇H₂₄N₄O₄ 
• 1311964-64-3 C₂₆H₄₀N₄O₈ 
• 1311960-88-9 C₂₇H₄₀N₄O₈ 
• 1178587-08-0 C₁₉H₃₁N₅O₃ 
• 1178587-03-5 C₃₂H₅₄N₄O₈Si 
• 1178587-02-4 C₃₉H₆₃N₇O₁₁ 
• 1178587-01-3 C₃₄H₅₅N₅O₉ 
• 1178586-99-6 MC₀₆₉A 
• 1178587-07-9 C₁₈H₂₉N₅O₂ 

Relevant articles and documents

BRD4-JAK2 INHIBITORS

Disclosed herein are compounds that are inhibitors of BDR4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BDR4 are also disclosed. In certain aspects, disclosed are compounds of Formula I through IV.

Fluorescence Properties and Exciplex Formation of Emissive Naphthyridine Derivatives: Application as Sensors for Amines

Water-soluble donor–acceptor-type fluorophore 15Nap-Cl having two trifluoromethyl groups and a Cl group on a 1,5-aminonaphthyridine framework was prepared. Fluorophore 15Nap-Cl showed strong solvatochromic fluorescence, and, as the solvent polarity increased, a bathochromic shift was observed accompanied by an increase in the fluorescence quantum yield. In addition, in the presence of amines such as ethylamine, diethylamine, and aniline, further considerable bathochromic shifts in the fluorescence were observed. Density functional calculations identified the source of the fluorescence behavior as exciplex formation between 15-Nap-Cl and the corresponding amine. The fluorescence behavior was exploited to fabricate a sensor that can identify various primary, secondary, and tertiary amines.

A modular approach to synthetic RNA binders of the hepatitis C virus internal ribosome entry site

(Figure Presented) DAPper ligands: The 3,5-diaminopiperidine (DAP) heterocycle has been developed as a structural mimetic of the RNA-recognizing pharmacophore of the 2-DOS scaffold. Here we describe the synthesis of novel modular DAP ligands that bind to a conformational target in the internal ribosome entry site RNA of the hepatitis C virus.

Pyridonecarboxylic acid derivatives or their salts and antibacterial agent comprising the same as the active ingredient

A pyridonecarboxylic acid derivative represented by the following general formula (1): STR1 [wherein R1 represents hydrogen atom or a carboxyl protective group; R2 represents hydroxyl group, a lower alkoxy group, or a substituted or unsubstituted amino group; R3 represents hydrogen atom or a halogen atom; R4 represents hydrogen atom or a halogen atom; R5 represents a halogen atom or an optionally substituted saturated cyclic amino group; R6 represents hydrogen atom, a halogen atom, nitro group, or an optionally protected amino group; X, Y and Z may be the same or different and respectively represent nitrogen atom, --CH= or --CR7 = (wherein R7 represents a lower alkyl group, a halogen atom, or cyano group) (with the proviso that at least one of X, Y and Z represent the nitrogen atom), and W represents nitrogen atom or --CR8 = (wherein R8 represents hydrogen atom, a halogen atom, or a lower alkyl group)] or its salt, as well as an antibacterial agent containing such compound are provided.